Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis

Rosario Luque-Martin, Jan Van den Bossche, Rebecca C. Furze, Annette E. Neele, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Sharon G. Bernard, Wouter J. de Jonge, Inmaculada Rioja, Rab K. Prinjha, Huw D. Lewis, Palwinder K. Mander, Menno P. J. de Winther*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number1242
Number of pages14
JournalFrontiers in Pharmacology
Volume10
DOIs
Publication statusPublished - 29 Oct 2019

Keywords

  • histone deacetylase
  • atherosclerosis
  • therapeutic targeting
  • monocyte
  • macrophage maturation
  • HDAC INHIBITORS
  • IN-VITRO
  • MACROPHAGES
  • RECEPTOR
  • CARBOXYLESTERASE
  • MECHANISMS
  • EXPRESSION
  • ARTHRITIS
  • ESTERASE
  • CANCER

Cite this

Luque-Martin, R., Van den Bossche, J., Furze, R. C., Neele, A. E., van der Velden, S., Gijbels, M. J. J., van Roomen, C. P. P. A., Bernard, S. G., de Jonge, W. J., Rioja, I., Prinjha, R. K., Lewis, H. D., Mander, P. K., & de Winther, M. P. J. (2019). Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis. Frontiers in Pharmacology, 10, [1242]. https://doi.org/10.3389/fphar.2019.01242