Tailoring treatment for women with heavy menstrual bleeding

Pleun Beelen

Research output: ThesisDoctoral ThesisInternal

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Around 30% of women experience heavy menstrual bleeding during their reproductive years and it is a common reason for consulting a gynecologist. Heavy menstrual bleeding has a negative impact on quality of life as it negatively influences physical activity, psychosocial well-being and sexual life. Two frequently used treatments are the levonorgestrel-releasing intrauterine system (LNG-IUS, Mirena®) and endometrial ablation (Novasure®). This dissertation focuses on the effectiveness of the LNG-IUS compared to endometrial ablation, whereby cost-effectiveness is also investigated. Furthermore, it provides insight into patient's preferences and it investigates if certain women have a higher risk of treatment failure with either the LNG-IUS or endometrial ablation. The results of the studies in this dissertation contribute to a tailor-made treatment for women with heavy menstrual bleeding.
Original languageEnglish
Awarding Institution
  • Maastricht University
  • Bongers, Marlies, Supervisor
  • Berger, M.Y., Supervisor, External person
  • Geomini, Peggy M. A. J., Co-Supervisor, External person
  • Herman, M.C., Co-Supervisor, External person
Award date7 May 2021
Place of PublicationMaastricht
Print ISBNs9789464164701
Publication statusPublished - 2021


  • Heavy menstrual bleeding
  • endometrial ablation
  • hormone coil
  • Novasure®
  • Mirena®

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