Systematic Review and Network Meta-Analysis on the Efficacy of Evolocumab and Other Therapies for the Management of Lipid Levels in Hyperlipidemia

Peter P. Toth*, Gillian Worthy, Shravanthi R. Gandra, Naveed Sattar, Sarah Bray, Lung-I Cheng, Ian Bridges, Gavin M. Worth, Ricardo Dent, Carol A. Forbes, Sohan Deshpande, Janine Ross, Jos Kleijnen, Erik S. G. Stroes

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Article numbere005367
Number of pages13
JournalJournal of the American Heart Association
Volume6
Issue number10
DOIs
Publication statusPublished - Oct 2017

Keywords

  • alirocumab
  • evidence-based medicine
  • evolocumab
  • ezetimibe
  • lipids
  • low-density lipoprotein cholesterol
  • meta-analysis
  • proprotein convertase subtilisin/kexin type 9 inhibitor
  • statin therapy
  • HIGH CARDIOVASCULAR-RISK
  • SUBTILISIN/KEXIN TYPE 9
  • HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
  • RANDOMIZED CONTROLLED-TRIAL
  • TREATED JAPANESE PATIENTS
  • ACUTE CORONARY SYNDROMES
  • ODYSSEY OPTIONS I
  • ISPOR TASK-FORCE
  • MONOCLONAL-ANTIBODY
  • STATIN THERAPY

Cite this

Toth, P. P., Worthy, G., Gandra, S. R., Sattar, N., Bray, S., Cheng, L-I., Bridges, I., Worth, G. M., Dent, R., Forbes, C. A., Deshpande, S., Ross, J., Kleijnen, J., & Stroes, E. S. G. (2017). Systematic Review and Network Meta-Analysis on the Efficacy of Evolocumab and Other Therapies for the Management of Lipid Levels in Hyperlipidemia. Journal of the American Heart Association, 6(10), [e005367]. https://doi.org/10.1161/JAHA.116.005367