Systematic Review and Network Meta-Analysis on the Efficacy of Evolocumab and Other Therapies for the Management of Lipid Levels in Hyperlipidemia

Peter P. Toth*, Gillian Worthy, Shravanthi R. Gandra, Naveed Sattar, Sarah Bray, Lung-I Cheng, Ian Bridges, Gavin M. Worth, Ricardo Dent, Carol A. Forbes, Sohan Deshpande, Janine Ross, Jos Kleijnen, Erik S. G. Stroes

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Article numbere005367
Number of pages13
JournalJournal of the American Heart Association
Volume6
Issue number10
DOIs
Publication statusPublished - Oct 2017

Keywords

  • alirocumab
  • evidence-based medicine
  • evolocumab
  • ezetimibe
  • lipids
  • low-density lipoprotein cholesterol
  • meta-analysis
  • proprotein convertase subtilisin/kexin type 9 inhibitor
  • statin therapy
  • HIGH CARDIOVASCULAR-RISK
  • SUBTILISIN/KEXIN TYPE 9
  • HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
  • RANDOMIZED CONTROLLED-TRIAL
  • TREATED JAPANESE PATIENTS
  • ACUTE CORONARY SYNDROMES
  • ODYSSEY OPTIONS I
  • ISPOR TASK-FORCE
  • MONOCLONAL-ANTIBODY
  • STATIN THERAPY

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