TY - JOUR
T1 - Systematic Evaluation of Lower Urinary Tract Sensations to Improve Management of LUTS
T2 - ICI-RS 2024
AU - de Rijk, Mathijs
AU - Hentzen, Claire
AU - Selai, Caroline
AU - Musco, Stefania
AU - Lombardo, Riccardo
AU - van Koeveringe, Gommert
AU - Chapple, Christopher
AU - Abrams, Paul
AU - Wyndaele, Jean J
AU - McCloskey, Karen
PY - 2024/12/16
Y1 - 2024/12/16
N2 - AIMS: Lower urinary tract (LUT) sensations form an essential part of diagnostic criteria for many LUT symptoms, additionally LUT sensations are used to evaluate the effectivity of therapeutic interventions. The accurate measurement of LUT sensations, however, is severely hampered by the subjective nature of these sensations. METHODS: This paper summarizes the discussions from the 2024 meeting of the International Consultation for Incontinence-Research Society (ICI-RS 2024) regarding systematic evaluations of LUT sensations and the design of more objective tools to measure these. RESULTS: Here, we discuss factors that influence sensations that are under the control of the caregiver/investigator, the signaling of sensations from the LUT toward the central nervous system, and currently used diagnostic tools to measure LUT sensations. Recent methodological advances to objectively measure factors that correspond with changes in LUT sensations are introduced along with recommendations for future research to optimally enable objective assessment of processes underlying LUT sensations. CONCLUSIONS: Advancing the objective measurement of LUT sensations will require interdisciplinary collaboration, integrating insights from neuroscience, engineering, and clinical practice. Such efforts hold the potential to transform patient care by enabling more precise diagnostics and personalized therapeutic strategies.
AB - AIMS: Lower urinary tract (LUT) sensations form an essential part of diagnostic criteria for many LUT symptoms, additionally LUT sensations are used to evaluate the effectivity of therapeutic interventions. The accurate measurement of LUT sensations, however, is severely hampered by the subjective nature of these sensations. METHODS: This paper summarizes the discussions from the 2024 meeting of the International Consultation for Incontinence-Research Society (ICI-RS 2024) regarding systematic evaluations of LUT sensations and the design of more objective tools to measure these. RESULTS: Here, we discuss factors that influence sensations that are under the control of the caregiver/investigator, the signaling of sensations from the LUT toward the central nervous system, and currently used diagnostic tools to measure LUT sensations. Recent methodological advances to objectively measure factors that correspond with changes in LUT sensations are introduced along with recommendations for future research to optimally enable objective assessment of processes underlying LUT sensations. CONCLUSIONS: Advancing the objective measurement of LUT sensations will require interdisciplinary collaboration, integrating insights from neuroscience, engineering, and clinical practice. Such efforts hold the potential to transform patient care by enabling more precise diagnostics and personalized therapeutic strategies.
KW - diagnostic tools
KW - lower urinary tract symptoms
KW - sensations
U2 - 10.1002/nau.25636
DO - 10.1002/nau.25636
M3 - (Systematic) Review article
SN - 0733-2467
JO - Neurourology and Urodynamics
JF - Neurourology and Urodynamics
ER -