Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo

Cees Vermeer; Cynthia van 'T Hoofd; Marjo H. J. Knapen; Sofia Xanthoulea

doi:10.1016/j.bmcl.2016.11.073

Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo

Cees Vermeer^*, Cynthia van 'T Hoofd, Marjo H. J. Knapen, Sofia Xanthoulea

^*Corresponding author for this work

Biochemie

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	208-211
Number of pages	4
Journal	Bioorganic & Medicinal Chemistry Letters
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/j.bmcl.2016.11.073
Publication status	Published - 15 Jan 2017

Keywords

2-Methyl-1,4-naphthoquinone
Vitamin K
Phylloquinone
Menaquinone
Osteocalcin
VITAMIN-K
PROTHROMBIN
ACID
PHYLLOQUINONE
ANALOGS
MATRIX
FOOD

Access to Document

10.1016/j.bmcl.2016.11.073

Cite this

@article{ec5d34e8d3134b47b4d360dc4648dfab,

title = "Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo",

keywords = "2-Methyl-1,4-naphthoquinone, Vitamin K, Phylloquinone, Menaquinone, Osteocalcin, VITAMIN-K, PROTHROMBIN, ACID, PHYLLOQUINONE, ANALOGS, MATRIX, FOOD",

author = "Cees Vermeer and {van 'T Hoofd}, Cynthia and Knapen, {Marjo H. J.} and Sofia Xanthoulea",

year = "2017",

month = jan,

day = "15",

doi = "10.1016/j.bmcl.2016.11.073",

language = "English",

volume = "27",

pages = "208--211",

journal = "Bioorganic & Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Science",

number = "2",

}

Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo. / Vermeer, Cees; van 'T Hoofd, Cynthia; Knapen, Marjo H. J.; Xanthoulea, Sofia.

In: Bioorganic & Medicinal Chemistry Letters, Vol. 27, No. 2, 15.01.2017, p. 208-211.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Synthesis of 2-methyl-1,4-naphthoquinones with higher gamma-glutamyl carboxylase activity than MK-4 both in vitro and in vivo

AU - Vermeer, Cees

AU - van 'T Hoofd, Cynthia

AU - Knapen, Marjo H. J.

AU - Xanthoulea, Sofia

PY - 2017/1/15

Y1 - 2017/1/15

KW - 2-Methyl-1,4-naphthoquinone

KW - Vitamin K

KW - Phylloquinone

KW - Menaquinone

KW - Osteocalcin

KW - VITAMIN-K

KW - PROTHROMBIN

KW - ACID

KW - PHYLLOQUINONE

KW - ANALOGS

KW - MATRIX

KW - FOOD

U2 - 10.1016/j.bmcl.2016.11.073

DO - 10.1016/j.bmcl.2016.11.073

M3 - Article

C2 - 27955810

VL - 27

SP - 208

EP - 211

JO - Bioorganic & Medicinal Chemistry Letters

JF - Bioorganic & Medicinal Chemistry Letters

SN - 0960-894X

IS - 2

ER -