Synthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogues

Keyphrases

• Thrombin Inhibitor 100%
• Sulfonate 100%
• Sulfotyrosine 100%
• Acid-stable 100%
• Peptidic 100%
• Post-translational Modification 50%
• Thrombin 50%
• Protein Modification 50%
• Protein-protein Interaction 50%
• Binding Mode 50%
• Mimicry 50%
• Peptide Modification 50%
• X-ray Crystallography 50%
• Sulfopeptide 50%
• Tyrosine Sulfation 50%
• Thrombin Inhibitory Activity 50%
• Inherent Instability 50%
• Mode of Activity 50%

INIS

• evaluation 100%
• proteins 100%
• synthesis 100%
• thrombin 100%
• modifications 66%
• sulfonates 66%
• tyrosine 33%
• interactions 33%
• instability 33%
• x radiation 33%
• peptides 33%
• crystallography 33%
• sulfation 33%

Biochemistry, Genetics and Molecular Biology

• Thrombin 100%
• Sulfonate 66%
• Posttranslational Modification 33%
• Protein-Protein Interaction 33%
• X-Ray Crystallography 33%
• Tyrosine Sulfation 33%