Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade

Erica Acquarone, Elentina K. Argyrousi, Manon van den Berg, Walter Gulisano, Mauro Fa, Agnieszka Staniszewski, Elisa Calcagno, Elisa Zuccarello, Luciano D'Adamio, Shi-Xian Deng, Daniela Puzzo, Ottavio Arancio*, Jole Fiorito*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number26
Number of pages19
JournalMolecular Neurodegeneration
Volume14
DOIs
Publication statusPublished - 27 Jun 2019

Keywords

  • Tau oligomers
  • Nitric oxide
  • Soluble guanylyl cyclase
  • PDE5
  • Protein kinase G
  • CREB
  • Memory
  • Alzheimer's disease
  • DEPENDENT PROTEIN-KINASE
  • LONG-TERM POTENTIATION
  • ELEMENT-BINDING PROTEIN
  • PHOSPHODIESTERASE 5 INHIBITOR
  • PAIRED HELICAL FILAMENTS
  • SELECTIVE PDE5 INHIBITOR
  • ALZHEIMERS-DISEASE
  • OBJECT MEMORY
  • MOUSE MODEL
  • ADENYLYL-CYCLASE

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