Survival after curative surgical treatment for primary oral squamous cell carcinoma

M Bloebaum, L Poort, R Böckmann, P Kessler

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

The purpose of this retrospective study was to review recurrence rate and survival of patients with primary oral squamous cell carcinoma (OSCC) that have received surgical treatment and adjuvant radio-therapy with curative intent in our clinic over a 6-year period. A total of 106 patients were included. The 5-year overall survival (OS) was 41%, 5-year disease-specific survival (DSS) was 77%, 5-year disease-free survival (DFS) was 72%. DSS was significantly different between early and advanced stage, 87% and 67% respectively (p = 0.04). Recurrence significantly affected survival: OS with or without recurrence at 20 months was 24% and 87% respectively (p < 0.001). Although a guideline based approach for the treatment of OSCC might provide an advantage, more data are needed for these guidelines to be based on.

Original languageEnglish
Pages (from-to)1572-6
Number of pages5
JournalJournal of Cranio-Maxillofacial Surgery
Volume42
Issue number8
DOIs
Publication statusPublished - Dec 2014

Keywords

  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents
  • Carcinoma, Squamous Cell
  • Cause of Death
  • Chemoradiotherapy, Adjuvant
  • Disease-Free Survival
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Mouth Neoplasms
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Survival Rate

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