Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

R. Molenkamp; E. Fanoy; L. Derickx; T. de Groot; M. Jonges; T. Leenstra; R. Nijhuis; S. Pas; A. Vahidnia; C. von Wintersdorff; B. Mulder; M. Koopmans

doi:10.2807/1560-7917.ES.2021.26.40.2100921

Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

R. Molenkamp^*, E. Fanoy, L. Derickx, T. de Groot, M. Jonges, T. Leenstra, R. Nijhuis, S. Pas, A. Vahidnia, C. von Wintersdorff, B. Mulder, M. Koopmans

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.

Original language	English
Article number	2100921
Number of pages	4
Journal	Eurosurveillance
Volume	26
Issue number	40
DOIs	https://doi.org/10.2807/1560-7917.ES.2021.26.40.2100921
Publication status	Published - 7 Oct 2021

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Molenkamp, R., Fanoy, E., Derickx, L., de Groot, T., Jonges, M., Leenstra, T., Nijhuis, R., Pas, S., Vahidnia, A., von Wintersdorff, C., Mulder, B., & Koopmans, M. (2021). Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021. Eurosurveillance, 26(40), Article 2100921. https://doi.org/10.2807/1560-7917.ES.2021.26.40.2100921

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abstract = "We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.",

author = "R. Molenkamp and E. Fanoy and L. Derickx and {de Groot}, T. and M. Jonges and T. Leenstra and R. Nijhuis and S. Pas and A. Vahidnia and {von Wintersdorff}, C. and B. Mulder and M. Koopmans",

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Molenkamp, R, Fanoy, E, Derickx, L, de Groot, T, Jonges, M, Leenstra, T, Nijhuis, R, Pas, S, Vahidnia, A, von Wintersdorff, C, Mulder, B & Koopmans, M 2021, 'Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021', Eurosurveillance, vol. 26, no. 40, 2100921. https://doi.org/10.2807/1560-7917.ES.2021.26.40.2100921

TY - JOUR

T1 - Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

AU - Molenkamp, R.

AU - Fanoy, E.

AU - Derickx, L.

AU - de Groot, T.

AU - Jonges, M.

AU - Leenstra, T.

AU - Nijhuis, R.

AU - Pas, S.

AU - Vahidnia, A.

AU - von Wintersdorff, C.

AU - Mulder, B.

AU - Koopmans, M.

PY - 2021/10/7

Y1 - 2021/10/7

N2 - We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.

AB - We evaluated routine testing with SARS-CoV-2 Delta variant-specific RT-PCR in regional hospital laboratories in addition to centralised national genomic surveillance in the Netherlands during June and July 2021. The increase of the Delta variant detected by RT-PCR correlated well with data from genomic surveillance and was available ca 2 weeks earlier. This rapid identification of the relative abundance and increase of SARS-CoV-2 variants of concern may have important benefits for implementation of local public health measures.

U2 - 10.2807/1560-7917.ES.2021.26.40.2100921

DO - 10.2807/1560-7917.ES.2021.26.40.2100921

M3 - Article

C2 - 34622759

SN - 1560-7917

VL - 26

JO - Eurosurveillance

JF - Eurosurveillance

IS - 40

M1 - 2100921

ER -

Supplementing SARS-CoV-2 genomic surveillance with PCR-based variant detection for real-time actionable information, the Netherlands, June to July 2021

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