Subtle blood-brain barrier leakage rate and spatial extent: Considerations for dynamic contrast-enhanced MRI

Harm J. van de Haar, Jacobus F. A. Jansen, Cecile R. L. P. N. Jeukens, Saartje Burgmans, Mark A. van Buchem, Majon Muller, Paul A. M. Hofman, Frans R. J. Verhey, Matthias J. P. van Osch, Walter H. Backes*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)4112-4125
Number of pages14
JournalMedical Physics
Volume44
Issue number8
DOIs
Publication statusPublished - Aug 2017

Keywords

  • Alzheimer's disease
  • blood-brain barrier
  • brain MRI
  • dynamic contrast-enhanced MRI
  • leakage
  • pharmacokinetic modeling
  • DCE-MRI
  • TEMPORAL RESOLUTION
  • ALZHEIMERS-DISEASE
  • IN-VIVO
  • 3 TESLA
  • PERMEABILITY
  • PARAMETERS
  • MODEL
  • QUANTIFICATION
  • ACQUISITION

Cite this

@article{9682cb0d65ff4f438e10718dfc0a341a,
title = "Subtle blood-brain barrier leakage rate and spatial extent: Considerations for dynamic contrast-enhanced MRI",
keywords = "Alzheimer's disease, blood-brain barrier, brain MRI, dynamic contrast-enhanced MRI, leakage, pharmacokinetic modeling, DCE-MRI, TEMPORAL RESOLUTION, ALZHEIMERS-DISEASE, IN-VIVO, 3 TESLA, PERMEABILITY, PARAMETERS, MODEL, QUANTIFICATION, ACQUISITION",
author = "{van de Haar}, {Harm J.} and Jansen, {Jacobus F. A.} and Jeukens, {Cecile R. L. P. N.} and Saartje Burgmans and {van Buchem}, {Mark A.} and Majon Muller and Hofman, {Paul A. M.} and Verhey, {Frans R. J.} and {van Osch}, {Matthias J. P.} and Backes, {Walter H.}",
year = "2017",
month = "8",
doi = "10.1002/mp.12328",
language = "English",
volume = "44",
pages = "4112--4125",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "Wiley",
number = "8",

}

Subtle blood-brain barrier leakage rate and spatial extent : Considerations for dynamic contrast-enhanced MRI. / van de Haar, Harm J.; Jansen, Jacobus F. A.; Jeukens, Cecile R. L. P. N.; Burgmans, Saartje; van Buchem, Mark A.; Muller, Majon; Hofman, Paul A. M.; Verhey, Frans R. J.; van Osch, Matthias J. P.; Backes, Walter H.

In: Medical Physics, Vol. 44, No. 8, 08.2017, p. 4112-4125.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Subtle blood-brain barrier leakage rate and spatial extent

T2 - Considerations for dynamic contrast-enhanced MRI

AU - van de Haar, Harm J.

AU - Jansen, Jacobus F. A.

AU - Jeukens, Cecile R. L. P. N.

AU - Burgmans, Saartje

AU - van Buchem, Mark A.

AU - Muller, Majon

AU - Hofman, Paul A. M.

AU - Verhey, Frans R. J.

AU - van Osch, Matthias J. P.

AU - Backes, Walter H.

PY - 2017/8

Y1 - 2017/8

KW - Alzheimer's disease

KW - blood-brain barrier

KW - brain MRI

KW - dynamic contrast-enhanced MRI

KW - leakage

KW - pharmacokinetic modeling

KW - DCE-MRI

KW - TEMPORAL RESOLUTION

KW - ALZHEIMERS-DISEASE

KW - IN-VIVO

KW - 3 TESLA

KW - PERMEABILITY

KW - PARAMETERS

KW - MODEL

KW - QUANTIFICATION

KW - ACQUISITION

U2 - 10.1002/mp.12328

DO - 10.1002/mp.12328

M3 - Article

VL - 44

SP - 4112

EP - 4125

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 8

ER -