Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Alexandre Slater, Ying Di, Joanne C. Clark, Natalie J. Jooss, Eleyna M. Martin, Fawaz Alenazy, Mark R. Thomas, Robert A. S. Ariens, Andrew B. Herr, Natalie S. Poulter, Jonas Emsley, Steve P. Watson

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)3443-3453
Number of pages11
JournalBlood
Volume137
Issue number24
DOIs
Publication statusPublished - 17 Jun 2021

Keywords

  • PLATELET GLYCOPROTEIN VI
  • RECEPTOR-GAMMA-CHAIN
  • SRC FAMILY KINASES
  • COLLAGEN
  • BINDING
  • DIMERIZATION
  • FIBRIN
  • ASSOCIATION
  • SITE
  • FYN

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