Structural and functional aspects of sensory-motor Interaction in the urinary bladder

Urinary incontinence is a social problem for various patients, particularly those with Alzheimer's disease. This dissertation aims to examine the sensory information and motor output of the bladder on a functional and structural level. A study was conducted using several animal models, including a model for Alzheimer's disease. Various sensory nerves were discovered in the bladder wall. Using functional studies, we were able to detect bladder contractions that indicate a local sensory-motor system in the bladder. We also discovered an unusual anatomy of the bladder wall and unusual urinary patters in the model for Alzheimer's disease.