Abstract
Urinary incontinence is a social problem for various patients, particularly those with Alzheimer's disease. This dissertation aims to examine the sensory information and motor output of the bladder on a functional and structural level. A study was conducted using several animal models, including a model for Alzheimer's disease. Various sensory nerves were discovered in the bladder wall. Using functional studies, we were able to detect bladder contractions that indicate a local sensory-motor system in the bladder. We also discovered an unusual anatomy of the bladder wall and unusual urinary patters in the model for Alzheimer's disease.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Supervisors/Advisors |
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Award date | 25 Sept 2015 |
Place of Publication | Maastricht |
Publisher | |
Print ISBNs | 9789090291949 |
DOIs | |
Publication status | Published - 2015 |
Keywords
- urinary incontinence
- Alzheimer's disease
- sensory information
- motor output