Structural and functional aspects of sensory-motor Interaction in the urinary bladder

B.T. Biallosterski

Research output: ThesisDoctoral ThesisInternal

328 Downloads (Pure)


Urinary incontinence is a social problem for various patients, particularly those with Alzheimer's disease. This dissertation aims to examine the sensory information and motor output of the bladder on a functional and structural level. A study was conducted using several animal models, including a model for Alzheimer's disease. Various sensory nerves were discovered in the bladder wall. Using functional studies, we were able to detect bladder contractions that indicate a local sensory-motor system in the bladder. We also discovered an unusual anatomy of the bladder wall and unusual urinary patters in the model for Alzheimer's disease.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • van Kerrebroeck, Philippe, Supervisor
  • de Wachter, S.G.G., Supervisor, External person
  • van Koeveringe, G.A., Co-Supervisor, External person
  • Rahnama’i, S., Co-Supervisor, External person
Award date25 Sep 2015
Place of PublicationMaastricht
Print ISBNs9789090291949
Publication statusPublished - 2015


  • urinary incontinence
  • Alzheimer's disease
  • sensory information
  • motor output

Cite this