Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

Cornelis J. M. Melief; Marij J. P. Welters; Ignace Vergote; Judith R. Kroep; Gemma G. Kenter; Petronella B. Ottevanger; Wiebren A. A. Tjalma; Hannelore Denys; Mariette I. E. van Poelgeest; Hans W. Nijman; Anna K. L. Reyners; Thierry Velu; Frederic Goffin; Roy Lalisang; Nikki M. Loof; Sanne Boekestijn; Willem Jan Krebber; Leon Hooftman; Sonja Visscher; Brent A. Blumenstein; Richard B. Stead; Winald Gerritsen; Sjoerd H. van der Burg

doi:10.1126/scitranslmed.aaz8235

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

Cornelis J. M. Melief^*, Marij J. P. Welters, Ignace Vergote, Judith R. Kroep, Gemma G. Kenter, Petronella B. Ottevanger, Wiebren A. A. Tjalma, Hannelore Denys, Mariette I. E. van Poelgeest, Hans W. Nijman, Anna K. L. Reyners, Thierry Velu, Frederic Goffin, Roy Lalisang, Nikki M. Loof, Sanne Boekestijn, Willem Jan Krebber, Leon Hooftman, Sonja Visscher, Brent A. BlumensteinRichard B. Stead, Winald Gerritsen, Sjoerd H. van der Burg^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	8235
Number of pages	12
Journal	Science Translational Medicine
Volume	12
Issue number	535
DOIs	https://doi.org/10.1126/scitranslmed.aaz8235
Publication status	Published - 18 Mar 2020

Keywords

REGULATORY T-CELLS
CERVICAL-CANCER
CLASS-I
CISPLATIN
E6
LEUKOCYTOSIS
CARBOPLATIN
INDUCTION
NIVOLUMAB
RECURRENT

Access to Document

10.1126/scitranslmed.aaz8235

Cite this

Melief, C. J. M., Welters, M. J. P., Vergote, I., Kroep, J. R., Kenter, G. G., Ottevanger, P. B., Tjalma, W. A. A., Denys, H., van Poelgeest, M. I. E., Nijman, H. W., Reyners, A. K. L., Velu, T., Goffin, F., Lalisang, R., Loof, N. M., Boekestijn, S., Krebber, W. J., Hooftman, L., Visscher, S., ... van der Burg, S. H. (2020). Strong vaccine responses during chemotherapy are associated with prolonged cancer survival. Science Translational Medicine, 12(535), [8235]. https://doi.org/10.1126/scitranslmed.aaz8235

Melief, Cornelis J. M. ; Welters, Marij J. P. ; Vergote, Ignace ; Kroep, Judith R. ; Kenter, Gemma G. ; Ottevanger, Petronella B. ; Tjalma, Wiebren A. A. ; Denys, Hannelore ; van Poelgeest, Mariette I. E. ; Nijman, Hans W. ; Reyners, Anna K. L. ; Velu, Thierry ; Goffin, Frederic ; Lalisang, Roy ; Loof, Nikki M. ; Boekestijn, Sanne ; Krebber, Willem Jan ; Hooftman, Leon ; Visscher, Sonja ; Blumenstein, Brent A. ; Stead, Richard B. ; Gerritsen, Winald ; van der Burg, Sjoerd H. / Strong vaccine responses during chemotherapy are associated with prolonged cancer survival. In: Science Translational Medicine. 2020 ; Vol. 12, No. 535.

@article{3221dc17f98c427f9b859687f4534519,

title = "Strong vaccine responses during chemotherapy are associated with prolonged cancer survival",

keywords = "REGULATORY T-CELLS, CERVICAL-CANCER, CLASS-I, CISPLATIN, E6, LEUKOCYTOSIS, CARBOPLATIN, INDUCTION, NIVOLUMAB, RECURRENT",

author = "Melief, {Cornelis J. M.} and Welters, {Marij J. P.} and Ignace Vergote and Kroep, {Judith R.} and Kenter, {Gemma G.} and Ottevanger, {Petronella B.} and Tjalma, {Wiebren A. A.} and Hannelore Denys and {van Poelgeest}, {Mariette I. E.} and Nijman, {Hans W.} and Reyners, {Anna K. L.} and Thierry Velu and Frederic Goffin and Roy Lalisang and Loof, {Nikki M.} and Sanne Boekestijn and Krebber, {Willem Jan} and Leon Hooftman and Sonja Visscher and Blumenstein, {Brent A.} and Stead, {Richard B.} and Winald Gerritsen and {van der Burg}, {Sjoerd H.}",

year = "2020",

month = mar,

day = "18",

doi = "10.1126/scitranslmed.aaz8235",

language = "English",

volume = "12",

journal = "Science Translational Medicine",

issn = "1946-6234",

publisher = "American Association for the Advancement of Science",

number = "535",

}

Melief, CJM, Welters, MJP, Vergote, I, Kroep, JR, Kenter, GG, Ottevanger, PB, Tjalma, WAA, Denys, H, van Poelgeest, MIE, Nijman, HW, Reyners, AKL, Velu, T, Goffin, F, Lalisang, R, Loof, NM, Boekestijn, S, Krebber, WJ, Hooftman, L, Visscher, S, Blumenstein, BA, Stead, RB, Gerritsen, W & van der Burg, SH 2020, 'Strong vaccine responses during chemotherapy are associated with prolonged cancer survival', Science Translational Medicine, vol. 12, no. 535, 8235. https://doi.org/10.1126/scitranslmed.aaz8235

Strong vaccine responses during chemotherapy are associated with prolonged cancer survival. / Melief, Cornelis J. M.; Welters, Marij J. P.; Vergote, Ignace; Kroep, Judith R.; Kenter, Gemma G.; Ottevanger, Petronella B.; Tjalma, Wiebren A. A.; Denys, Hannelore; van Poelgeest, Mariette I. E.; Nijman, Hans W.; Reyners, Anna K. L.; Velu, Thierry; Goffin, Frederic; Lalisang, Roy; Loof, Nikki M.; Boekestijn, Sanne; Krebber, Willem Jan; Hooftman, Leon; Visscher, Sonja; Blumenstein, Brent A.; Stead, Richard B.; Gerritsen, Winald; van der Burg, Sjoerd H.

In: Science Translational Medicine, Vol. 12, No. 535, 8235, 18.03.2020.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Strong vaccine responses during chemotherapy are associated with prolonged cancer survival

AU - Melief, Cornelis J. M.

AU - Welters, Marij J. P.

AU - Vergote, Ignace

AU - Kroep, Judith R.

AU - Kenter, Gemma G.

AU - Ottevanger, Petronella B.

AU - Tjalma, Wiebren A. A.

AU - Denys, Hannelore

AU - van Poelgeest, Mariette I. E.

AU - Nijman, Hans W.

AU - Reyners, Anna K. L.

AU - Velu, Thierry

AU - Goffin, Frederic

AU - Lalisang, Roy

AU - Loof, Nikki M.

AU - Boekestijn, Sanne

AU - Krebber, Willem Jan

AU - Hooftman, Leon

AU - Visscher, Sonja

AU - Blumenstein, Brent A.

AU - Stead, Richard B.

AU - Gerritsen, Winald

AU - van der Burg, Sjoerd H.

PY - 2020/3/18

Y1 - 2020/3/18

KW - REGULATORY T-CELLS

KW - CERVICAL-CANCER

KW - CLASS-I

KW - CISPLATIN

KW - E6

KW - LEUKOCYTOSIS

KW - CARBOPLATIN

KW - INDUCTION

KW - NIVOLUMAB

KW - RECURRENT

U2 - 10.1126/scitranslmed.aaz8235

DO - 10.1126/scitranslmed.aaz8235

M3 - Article

C2 - 32188726

VL - 12

JO - Science Translational Medicine

JF - Science Translational Medicine

SN - 1946-6234

IS - 535

M1 - 8235

ER -