Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine

S. A. J. M. van Riel*, A. J. R. Balthasar, S. M. Schalla, M. A. Siemonsma, W. N. K. A. van Mook

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

A 48-year-old healthy female underwent an uncomplicated right ovariectomy. Relaxation status was checked post-surgery. A train of four of 2 of 4 twitches was scored. At this point, 5000 mu g of norepinephrine was erroneously administered instead of 2500 mu g neostigmine along with 1000 mu g of atropine. The postoperative period was complicated by pulmonary oedema, for which non-invasive mechanical ventilation was initiated in the intensive care unit. A transthoracic echocardiogram TTE revealed a left ventricular ejection fraction of 25%. One month after discharge, control TTE showed normalised systolic cardiac function.
Original languageEnglish
Pages (from-to)194-197
Number of pages4
JournalNetherlands Journal of Critical Care
Volume26
Issue number5
Publication statusPublished - 1 Sept 2018

Keywords

  • cardiomyopathy
  • norepinephrine
  • medication error
  • INDUCED MYOCARDIAL NECROSIS
  • ALPHA-ADRENERGIC BLOCKADE
  • PULMONARY-EDEMA
  • HEART-FAILURE
  • ISOPROTERENOL
  • PHEOCHROMOCYTOMA
  • ASSOCIATION
  • ANESTHESIA
  • RATS

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