Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine

S. A. J. M. van Riel; A. J. R. Balthasar; S. M. Schalla; M. A. Siemonsma; W. N. K. A. van Mook

Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine

S. A. J. M. van Riel^*, A. J. R. Balthasar, S. M. Schalla, M. A. Siemonsma, W. N. K. A. van Mook

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

A 48-year-old healthy female underwent an uncomplicated right ovariectomy. Relaxation status was checked post-surgery. A train of four of 2 of 4 twitches was scored. At this point, 5000 mu g of norepinephrine was erroneously administered instead of 2500 mu g neostigmine along with 1000 mu g of atropine. The postoperative period was complicated by pulmonary oedema, for which non-invasive mechanical ventilation was initiated in the intensive care unit. A transthoracic echocardiogram TTE revealed a left ventricular ejection fraction of 25%. One month after discharge, control TTE showed normalised systolic cardiac function.

Original language	English
Pages (from-to)	194-197
Number of pages	4
Journal	Netherlands Journal of Critical Care
Volume	26
Issue number	5
Publication status	Published - 1 Sept 2018

Keywords

cardiomyopathy
norepinephrine
medication error
INDUCED MYOCARDIAL NECROSIS
ALPHA-ADRENERGIC BLOCKADE
PULMONARY-EDEMA
HEART-FAILURE
ISOPROTERENOL
PHEOCHROMOCYTOMA
ASSOCIATION
ANESTHESIA
RATS

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@article{ec003e2a1342481b8ce3e71c9b5e9f87,

title = "Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine",

abstract = "A 48-year-old healthy female underwent an uncomplicated right ovariectomy. Relaxation status was checked post-surgery. A train of four of 2 of 4 twitches was scored. At this point, 5000 mu g of norepinephrine was erroneously administered instead of 2500 mu g neostigmine along with 1000 mu g of atropine. The postoperative period was complicated by pulmonary oedema, for which non-invasive mechanical ventilation was initiated in the intensive care unit. A transthoracic echocardiogram TTE revealed a left ventricular ejection fraction of 25%. One month after discharge, control TTE showed normalised systolic cardiac function.",

keywords = "cardiomyopathy, norepinephrine, medication error, INDUCED MYOCARDIAL NECROSIS, ALPHA-ADRENERGIC BLOCKADE, PULMONARY-EDEMA, HEART-FAILURE, ISOPROTERENOL, PHEOCHROMOCYTOMA, ASSOCIATION, ANESTHESIA, RATS",

author = "{van Riel}, {S. A. J. M.} and Balthasar, {A. J. R.} and Schalla, {S. M.} and Siemonsma, {M. A.} and {van Mook}, {W. N. K. A.}",

year = "2018",

month = sep,

day = "1",

language = "English",

volume = "26",

pages = "194--197",

journal = "Netherlands Journal of Critical Care",

issn = "1569-3511",

publisher = "Netherlands Society for Intensive Care,Nederlandse Vereniging voor Intensive Care",

number = "5",

}

TY - JOUR

T1 - Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine

AU - van Riel, S. A. J. M.

AU - Balthasar, A. J. R.

AU - Schalla, S. M.

AU - Siemonsma, M. A.

AU - van Mook, W. N. K. A.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - A 48-year-old healthy female underwent an uncomplicated right ovariectomy. Relaxation status was checked post-surgery. A train of four of 2 of 4 twitches was scored. At this point, 5000 mu g of norepinephrine was erroneously administered instead of 2500 mu g neostigmine along with 1000 mu g of atropine. The postoperative period was complicated by pulmonary oedema, for which non-invasive mechanical ventilation was initiated in the intensive care unit. A transthoracic echocardiogram TTE revealed a left ventricular ejection fraction of 25%. One month after discharge, control TTE showed normalised systolic cardiac function.

AB - A 48-year-old healthy female underwent an uncomplicated right ovariectomy. Relaxation status was checked post-surgery. A train of four of 2 of 4 twitches was scored. At this point, 5000 mu g of norepinephrine was erroneously administered instead of 2500 mu g neostigmine along with 1000 mu g of atropine. The postoperative period was complicated by pulmonary oedema, for which non-invasive mechanical ventilation was initiated in the intensive care unit. A transthoracic echocardiogram TTE revealed a left ventricular ejection fraction of 25%. One month after discharge, control TTE showed normalised systolic cardiac function.

KW - cardiomyopathy

KW - norepinephrine

KW - medication error

KW - INDUCED MYOCARDIAL NECROSIS

KW - ALPHA-ADRENERGIC BLOCKADE

KW - PULMONARY-EDEMA

KW - HEART-FAILURE

KW - ISOPROTERENOL

KW - PHEOCHROMOCYTOMA

KW - ASSOCIATION

KW - ANESTHESIA

KW - RATS

M3 - Article

SN - 1569-3511

VL - 26

SP - 194

EP - 197

JO - Netherlands Journal of Critical Care

JF - Netherlands Journal of Critical Care

IS - 5

ER -

Stress-induced transient cardiomyopathy due to accidental administration of norepinephrine

Abstract

Keywords

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