Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain

Jeroen F. J. Bogie*, Elien Grajchen, Elien Wouters, Aida Garcia Corrales, Tess Dierckx, Sam Vanherle, Jo Mailleux, Pascal Gervois, Esther Wolfs, Jonas Dehairs, Jana Van Broeckhoven, Andrew P. Bowman, Ivo Lambrichts, Jan-Ake Gustafsson, Alan T. Remaley, Monique Mulder, Johannes Swinnen, Mansour Haidar, Shane R. Ellis, James M. NtambiNoam Zelcer, Jerome J. A. Hendriks*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number20191660
Number of pages26
JournalJournal of Experimental Medicine
Volume217
Issue number5
DOIs
Publication statusPublished - May 2020

Keywords

  • CHOLESTEROL EFFLUX
  • MYELIN PHAGOCYTOSIS
  • FATTY-ACIDS
  • ELECTROSPRAY-IONIZATION
  • STIMULATED MACROPHAGES
  • DEFICIENCY PROTECTS
  • GENE-EXPRESSION
  • FOAM CELLS
  • MICE
  • REMYELINATION

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