Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain

Jeroen F. J. Bogie, Elien Grajchen, Elien Wouters, Aida Garcia Corrales, Tess Dierckx, Sam Vanherle, Jo Mailleux, Pascal Gervois, Esther Wolfs, Jonas Dehairs, Jana Van Broeckhoven, Andrew P. Bowman, Ivo Lambrichts, Jan-Ake Gustafsson, Alan T. Remaley, Monique Mulder, Johannes Swinnen, Mansour Haidar, Shane R. Ellis, James M. NtambiNoam Zelcer, Jerome J. A. Hendriks

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number20191660
Number of pages26
JournalJournal of Experimental Medicine
Volume217
Issue number5
DOIs
Publication statusPublished - May 2020

Keywords

  • CHOLESTEROL EFFLUX
  • MYELIN PHAGOCYTOSIS
  • FATTY-ACIDS
  • ELECTROSPRAY-IONIZATION
  • STIMULATED MACROPHAGES
  • DEFICIENCY PROTECTS
  • GENE-EXPRESSION
  • FOAM CELLS
  • MICE
  • REMYELINATION

Cite this

Bogie, J. F. J., Grajchen, E., Wouters, E., Corrales, A. G., Dierckx, T., Vanherle, S., Mailleux, J., Gervois, P., Wolfs, E., Dehairs, J., Van Broeckhoven, J., Bowman, A. P., Lambrichts, I., Gustafsson, J-A., Remaley, A. T., Mulder, M., Swinnen, J., Haidar, M., Ellis, S. R., ... Hendriks, J. J. A. (2020). Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain. Journal of Experimental Medicine, 217(5), [20191660]. https://doi.org/10.1084/jem.20191660