Startle reactivity and prepulse inhibition of the acoustic startle response are modulated by catechol-O-methyl-transferase Val(158) Met polymorphism in adults with 22q11 deletion syndrome

Mariken B. de Koning*, Erik Boot, Oswald J. N. Bloemen, Esther D. A. van Duin, Kathryn M. Abel, Lieuwe de Haan, Don H. Linszen, Therese A. M. J. van Amelsvoort

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1548-1560
JournalJournal of Psychopharmacology
Issue number12
Publication statusPublished - Dec 2012


  • Dopamine
  • COMT
  • 22q11 deletion syndrome
  • velo-cardio-facial syndrome
  • prepulse inhibition
  • startle reactivity

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