Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo

John T. Heap, Jan Theys, Muhammad Ehsaan, Aleksandra M. Kubiak, Ludwig Dubois, Kim Paesmans, Lieve Van Mellaert, Richard Knox, Sarah A. Kuehne, Phillipe Lambin, Nigel P. Minton*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Web of Science)
2 Downloads (Pure)
Original languageEnglish
Pages (from-to)1761-1769
JournalOncotarget
Volume5
Issue number7
DOIs
Publication statusPublished - Apr 2014

Keywords

  • Clostridia
  • spores
  • hypoxia
  • pro-drug converting enzyme
  • nitroreductase
  • CB1954
  • solid tumor

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