Spontaneous regression and recurrence of stage III Merkel cell carcinoma

Sandra Catharina Petronella Jansen; Christine P M Groeneveld-Haenen; Paul J J M Klinkhamer; Rudi M H Roumen

doi:10.1136/bcr-2014-208344

Spontaneous regression and recurrence of stage III Merkel cell carcinoma

Sandra Catharina Petronella Jansen^*, Christine P M Groeneveld-Haenen, Paul J J M Klinkhamer, Rudi M H Roumen

^*Corresponding author for this work

GROW - Innovative Cancer Diagnostics & Therapy

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.

Original language	English
Journal	BMJ case Reports
Volume	2015
DOIs	https://doi.org/10.1136/bcr-2014-208344
Publication status	Published - 25 Feb 2015

Keywords

Carcinoma, Merkel Cell
Female
Groin
Humans
Lymph Node Excision
Lymph Nodes
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Regression, Spontaneous
Neoplasm Staging
Radiotherapy, Adjuvant
Skin Neoplasms
Treatment Outcome

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title = "Spontaneous regression and recurrence of stage III Merkel cell carcinoma",

abstract = "Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.",

keywords = "Carcinoma, Merkel Cell, Female, Groin, Humans, Lymph Node Excision, Lymph Nodes, Middle Aged, Neoplasm Recurrence, Local, Neoplasm Regression, Spontaneous, Neoplasm Staging, Radiotherapy, Adjuvant, Skin Neoplasms, Treatment Outcome",

author = "Jansen, {Sandra Catharina Petronella} and Groeneveld-Haenen, {Christine P M} and Klinkhamer, {Paul J J M} and Roumen, {Rudi M H}",

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T1 - Spontaneous regression and recurrence of stage III Merkel cell carcinoma

AU - Jansen, Sandra Catharina Petronella

AU - Groeneveld-Haenen, Christine P M

AU - Klinkhamer, Paul J J M

AU - Roumen, Rudi M H

N1 - 2015 BMJ Publishing Group Ltd.

PY - 2015/2/25

Y1 - 2015/2/25

N2 - Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.

AB - Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.

KW - Carcinoma, Merkel Cell

KW - Female

KW - Groin

KW - Humans

KW - Lymph Node Excision

KW - Lymph Nodes

KW - Middle Aged

KW - Neoplasm Recurrence, Local

KW - Neoplasm Regression, Spontaneous

KW - Neoplasm Staging

KW - Radiotherapy, Adjuvant

KW - Skin Neoplasms

KW - Treatment Outcome

U2 - 10.1136/bcr-2014-208344

DO - 10.1136/bcr-2014-208344

M3 - Article

C2 - 25716042

SN - 1757-790X

VL - 2015

JO - BMJ case Reports

JF - BMJ case Reports

ER -

Spontaneous regression and recurrence of stage III Merkel cell carcinoma

Abstract

Keywords

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