Spontaneous regression and recurrence of stage III Merkel cell carcinoma

Sandra Catharina Petronella Jansen, Christine P M Groeneveld-Haenen, Paul J J M Klinkhamer, Rudi M H Roumen

Research output: Contribution to journalArticleAcademicpeer-review


Merkel cell carcinoma (MCC) is a malignant neuroendocrine carcinoma originating in the skin. It is typically aggressive with a tendency to recur locally and metastasise. There have been several case reports about spontaneous regression of MCC over the past years, but to the best of our knowledge this is the first case of a regional lymph node metastasised MCC with complete spontaneous regression and recurrence. In addition, the primary tumour has an unusual localisation on the foot.

Original languageEnglish
JournalBMJ case Reports
Publication statusPublished - 25 Feb 2015


  • Carcinoma, Merkel Cell
  • Female
  • Groin
  • Humans
  • Lymph Node Excision
  • Lymph Nodes
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Neoplasm Regression, Spontaneous
  • Neoplasm Staging
  • Radiotherapy, Adjuvant
  • Skin Neoplasms
  • Treatment Outcome

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