Spontaneous coronary artery dissections and associated predisposing factors: anarrative review

E. B. N. J. Janssen, P. W. de Leeuw, A. H. E. M. Maas*

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Spontaneous coronary artery dissection (SCAD) represents around 25% of cases of acute coronary syndromes (ACS) in women aged 40-65years who have few or no traditional cardiovascular risk factors. It is assumed that the incidence is underestimated, as the angiographic appearance of SCAD may often mimic atherosclerosis. This review aims to examine SCAD by focusing on the associated predisposing factors and precipitating stressors in this heterogeneous patient population, as well as the best treatment approach and the prognosis. Progressive knowledge has improved our current understanding of SCAD, but more awareness among clinicians is necessary. Recently, two position papers from the European Society of Cardiology (ESC) and the American Heart Association (AHA) have been released, which will be summarised in brief.

Original languageEnglish
Pages (from-to)246-251
Number of pages6
JournalNetherlands Heart Journal
Volume27
Issue number5
DOIs
Publication statusPublished - May 2019

Keywords

  • Spontaneous coronary artery dissection
  • Acute coronary syndrome
  • Myocardial infarction
  • Fibromuscular dysplasia
  • Women
  • ACUTE MYOCARDIAL-INFARCTION
  • FIBROMUSCULAR DYSPLASIA
  • PREVALENCE
  • MANAGEMENT
  • STRESSORS
  • ANEURYSM
  • TRIGGERS
  • REGISTRY
  • WOMEN

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