Abstract
Objective: We investigated the potential of a high-protein, arginine- and micronutrient-enriched oral nutritional supplement (ONS) to improve healing of pressure ulcers in non-malnourished patients who would usually not be considered for extra nutritional support. Methods: Forty-three non-malnourished subjects with stage III or IV pressure ulcers were included in a multicountry, randomized, controlled, double-blind, parallel group trial. They were offered 200 mL of the specific ONS or a non-caloric control product three times per day, in addition to their regular diet and standard wound care, for a maximum of 8 wk. Results were compared with repeated-measures mixed models (RMMM), analysis of variance, or Fisher's exact tests for categorical parameters. Results: Supplementation with the specific ONS accelerated pressure ulcer healing, indicated by a significantly different decrease in ulcer size compared with the control, over the period of 8 wk (P
Original language | English |
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Pages (from-to) | 867-872 |
Journal | Nutrition |
Volume | 26 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sept 2010 |
Keywords
- Pressure ulcers
- Oral nutritional supplement
- Non-malnourished
- Protein
- Arginine
- Zinc
- Vitamins