TY - JOUR
T1 - Spatial distribution and determinants of the knowledge of reproductive age women about prevention of mother to child transmission (PMTCT) of HIV in Ethiopia
AU - Belete, Abebe Gedefaw
AU - Getahun, Genanew Kassie
AU - Seid, Kedir
AU - Jaleta, Chala Getaneh
AU - Lorato, Sintayehu Samuel
AU - Desalegn, Mitiku
AU - Rundasa, Dawit Tesfaye
AU - Ashebir, Yohannes Godie
AU - Getahun, Olyad Kuma
AU - Lakew, Gebeyehu
AU - Gemmechu, Mathewos Mekonnen
AU - Zeleke, Mulualem Endeshaw
AU - Atalay, Yibeltal Assefa
AU - Yirsaw, Amlaku Nigusie
AU - Bogale, Eyob Ketema
AU - Tikuneh, Abiy Hailu
AU - Hassen, Abas Ali
AU - Lake, Eyasu Alem
AU - Nigussie, Tadesse
AU - Teshale, Manaye Yihune
AU - Belete, Nigus Kabtu
AU - Hailegebreal, Samuel
AU - Fornah, Lovel
AU - Gabriel, Abakundana Nsenga Ariston
AU - Shimbre, Mulugeta Shegaze
AU - Bibi, Bushra
AU - Jaleta, Fikiru Yigezu
PY - 2025/12/8
Y1 - 2025/12/8
N2 - IntroductionLimited knowledge about preventing mother-to-child transmission of HIV contributes to the high prevalence of pediatric HIV caused by vertical transmission. Given the lack of sufficient information, this study aimed to identify hotspot and cold spot areas as well as the factors influencing reproductive-age women's knowledge about preventing mother-to-child transmission of HIV in Ethiopia.MethodThe study utilized data from the 2016 Ethiopian Demographic and Health Survey, comprising a weighted sample of 15,683 reproductive-age women. Spatial analysis was conducted to identify significant clusters, and determinants were assessed using adjusted odds ratios with 95% confidence intervals.ResultSignificant hotspot regions were identified in Somali, Gambela, Afar, Benishangul Gumuz, the northern part of SNNP, and certain areas of Oromia. Key determinants included education level (primary: AOR = 1.19, 95% CI = 1.02-1.40; secondary: AOR = 1.41, 95% CI = 1.08-1.85; higher: AOR = 2.22, 95% CI = 1.52-3.25), religious affiliation (Muslim: AOR = 0.57, 95% CI = 0.47-0.68; Protestant: AOR = 0.76, 95% CI = 0.61-0.93; Other: AOR = 0.54, 95% CI = 0.33-0.86), having an employed partner (AOR = 1.36, 95% CI = 1.08-1.71), higher wealth index (rich: AOR = 1.35, 95% CI = 1.11-1.63), media exposure (AOR = 1.32, 95% CI = 1.12-1.57), antenatal care attendance (AOR = 1.46, 95% CI = 1.25-1.70), institutional childbirth (AOR = 1.18, 95% CI = 1.01-1.37), urban living (AOR = 1.36, 95% CI = 1.01-1.83), residence in larger central regions (AOR = 1.38, 95% CI = 1.12-1.70), and living in communities with high media exposure (AOR = 1.41, 95% CI = 1.13-1.75).ConclusionIn Ethiopia, knowledge about preventing mother-to-child transmission of HIV among women of reproductive age varies significantly across regions. Therefore, implementing targeted interventions in the identified hotspot areas is essential to support the WHO's goal of eliminating new pediatric HIV infections by 2030.
AB - IntroductionLimited knowledge about preventing mother-to-child transmission of HIV contributes to the high prevalence of pediatric HIV caused by vertical transmission. Given the lack of sufficient information, this study aimed to identify hotspot and cold spot areas as well as the factors influencing reproductive-age women's knowledge about preventing mother-to-child transmission of HIV in Ethiopia.MethodThe study utilized data from the 2016 Ethiopian Demographic and Health Survey, comprising a weighted sample of 15,683 reproductive-age women. Spatial analysis was conducted to identify significant clusters, and determinants were assessed using adjusted odds ratios with 95% confidence intervals.ResultSignificant hotspot regions were identified in Somali, Gambela, Afar, Benishangul Gumuz, the northern part of SNNP, and certain areas of Oromia. Key determinants included education level (primary: AOR = 1.19, 95% CI = 1.02-1.40; secondary: AOR = 1.41, 95% CI = 1.08-1.85; higher: AOR = 2.22, 95% CI = 1.52-3.25), religious affiliation (Muslim: AOR = 0.57, 95% CI = 0.47-0.68; Protestant: AOR = 0.76, 95% CI = 0.61-0.93; Other: AOR = 0.54, 95% CI = 0.33-0.86), having an employed partner (AOR = 1.36, 95% CI = 1.08-1.71), higher wealth index (rich: AOR = 1.35, 95% CI = 1.11-1.63), media exposure (AOR = 1.32, 95% CI = 1.12-1.57), antenatal care attendance (AOR = 1.46, 95% CI = 1.25-1.70), institutional childbirth (AOR = 1.18, 95% CI = 1.01-1.37), urban living (AOR = 1.36, 95% CI = 1.01-1.83), residence in larger central regions (AOR = 1.38, 95% CI = 1.12-1.70), and living in communities with high media exposure (AOR = 1.41, 95% CI = 1.13-1.75).ConclusionIn Ethiopia, knowledge about preventing mother-to-child transmission of HIV among women of reproductive age varies significantly across regions. Therefore, implementing targeted interventions in the identified hotspot areas is essential to support the WHO's goal of eliminating new pediatric HIV infections by 2030.
KW - Knowledge
KW - Spatial distribution
KW - Prevention of mother-to-child transmission
KW - PMTCT
KW - Reproductive age women
KW - Ethiopia
KW - HEALTH
U2 - 10.1186/s12981-025-00829-2
DO - 10.1186/s12981-025-00829-2
M3 - Article
SN - 1742-6405
VL - 23
JO - AIDS Research and Therapy
JF - AIDS Research and Therapy
IS - 1
M1 - 8
ER -