SPARC preserves endothelial glycocalyx integrity, and protects against adverse cardiac inflammation and injury during viral myocarditis

Marieke Rienks*, Paolo Carai, Jurgen van Teeffelen, Bart Eskens, Wouter Verhesen, Bianca Hemmeryckx, Daniel M. Johnson, Rick van Leeuwen, Elizabeth A. Jones, Stephane Heymans, Anna-Pia Papageorgiou

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)21-34
Number of pages14
JournalMatrix Biology
Volume74
DOIs
Publication statusPublished - Dec 2018

Keywords

  • SPARC
  • Endothelial glycocalyx
  • Viral myocarditis
  • Extracellular matrix
  • Inflammation
  • FIBRILLAR COLLAGEN CONTENT
  • DIASTOLIC FUNCTION ROLE
  • PHENOTYPIC HETEROGENEITY
  • EXTRACELLULAR-MATRIX
  • PRESSURE-OVERLOAD
  • HEPARAN-SULFATE
  • AGE
  • ANGIOGENESIS
  • ACTIVATION
  • FIBROSIS

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