Abstract

How are tactile sensations in the breast represented in the female and male brain? Using ultra high-field 7 T MRI in ten females and ten males, we demonstrate that the representation of tactile breast information shows a somatotopic organization, with cortical magnification of the nipple. Furthermore, we show that the core representation of the breast is organized according to the specific nerve architecture that underlies breast sensation, where the medial and lateral sides of one breast are asymmetrically represented in bilateral primary somatosensory cortex. Finally, gradual selectivity signatures allude to a somatotopic organization of the breast area with overlapping, but distinctive, cortical representations of breast segments. Our univariate and multivariate analyses consistently showed similar somatosensory breast representations in males and females. The findings can guide future research on neuroplastic reorganization of the breast area, across reproductive life stages, and after breast surgery.

Original languageEnglish
Article number116201
Number of pages8
JournalNeuroimage
Volume204
Early online date18 Sep 2019
DOIs
Publication statusPublished - 1 Jan 2020

Keywords

  • Somatosensory cortex
  • Somatotopy
  • Neuroplasticity
  • Breast
  • Breast sensation
  • Tactile processing
  • Ultra high-field functional MRI
  • NIPPLE-AREOLA COMPLEX
  • SOMATOSENSORY CORTEX
  • VISUAL-CORTEX
  • REPRESENTATION
  • FMRI
  • PREVALENCE
  • SUBJECT
  • PAIN

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