@article{a36b2848a28040b4bdcfd3f5979d57de,
title = "Sleep apnoea is associated with hearing impairment: The Paris prospective study 3",
abstract = "Objectives Hearing impairment (HI) is a leading impairment worldwide, and identifying modifiable risk factors of HI may have major public health implications. The aim of this study was to investigate the association between obstructive sleep apnoea (OSA) and HI.Design Observational longitudinal study (the Paris Prospective Study 3).Setting Population-based.Participants Volunteers aged 50-75 years and consulting at a preventive medical centre were included between 2008 and 2012. 6797 participants were included in the present analysis.Main outcome measures Audiometry testing was performed in both ears in all participants, and HI was defined by a pure-tone average (PTA) >25 decibels (dB) hearing level in the better ear.Results Obstructive sleep apnoea (estimated by the Berlin questionnaire) was present in 18.6% (n = 1267) and HI in 13.9% (n = 947) of the participants. Mean age was 59.5 years (SD 6.2) and 63.5% were male (n = 4317). In multiple logistic regression modelling, OSA was significantly associated with a 1.21-increased odds of HI (95% confidence interval 1.01-1.44). Several sensitivity analyses supported this finding.Conclusion Obstructive sleep apnoea is associated with a 21% increased odds of HI. These results support active screening of HI in subjects with OSA, and future studies should evaluate whether the treatment of OSA can delay the onset of HI.",
keywords = "cohort study, hearing impairment, sleep apnoea, BERLIN QUESTIONNAIRE, PREVALENCE, RISK, MICE",
author = "Quentin Lisan and {van Sloten}, Thomas and Climie, {Rachel E.} and Pierre Boutouyrie and Catherine Guibout and Frederique Thomas and Nicolas Danchin and Xavier Jouven and Jean-Philippe Empana",
note = "Funding Information: The PPS3 Study was supported by grants from the National Research Agency (ANR), the Research Foundation for Hypertension (RFHTA), the Research Institute in Public Health (IRESP) and the Region Ile de France (Domaine d'Int{\'e}r{\^e}t Majeur). Funding Information: The PPS3 Study was supported by grants from the National Research Agency (ANR), the Research Foundation for Hypertension (RFHTA), the Research Institute in Public Health (IRESP) and the Region Ile de France (Domaine d'Int?r?t Majeur). We thank N. Estrugo, S. Yanes, JF Pruny and J. Lacet Machado for performing the study recruitment of PPS3 study participants, Dr MF Eprinchard, Dr JM Kirzin and all the medical and technical staff of the IPC Center, the Centre de Ressources Biologiques of the European Hospital Georges Pompidou staff (C. de Toma, B. Vedie), and the Platform for Biological Resources (PRB) of the European Hospital Georges Pompidou for the management of the biobank. The PPS3 is organised under an agreement between INSERM and the IPC Center, and between INSERM and the Ressources Biologiques of European Hospital Georges Pompidou, Paris, France. We also thank the Caisse Nationale d'Assurance Maladie des Travailleurs Salari?s (CNAM-TS, France) and the Caisse Primaire d'Assurance Maladie de Paris (CPAM-P, France) for helping make this study possible. Publisher Copyright: {\textcopyright} 2020 John Wiley & Sons Ltd",
year = "2020",
month = sep,
doi = "10.1111/coa.13557",
language = "English",
volume = "45",
pages = "681--686",
journal = "Clinical Otolaryngology",
issn = "1749-4478",
publisher = "Wiley",
number = "5",
}