Skin cancers are the most frequent cancers in fair-skinned populations, but we can prevent them

Claus Garbe*, Ana Maria Forsea, Teresa Amaral, Petr Arenberger, Philippe Autier, Marianne Berwick, Brigitta Boonen, Matilda Bylaite, Veronique del Marmol, Brigitte Dreno, Maria Concetta Fargnoli, Alan C. Geller, Adele C. Green, Rüdiger Greinert, Axel Hauschild, Catherine A. Harwood, Isabelle Hoorens, Lidija Kandolf, Roland Kaufmann, Nicole Kelleners-SmeetsAimilios Lallas, Celeste Lebbé, Ulrike Leiter, Henry W. Lim, Caterina Longo, Joseph Malvehy, David Moreno, Giovanni Pellacani, Ketty Peris, Caroline Robert, Philippe Saiag, Dirk Schadendorf, H. Peter Soyer, Eggert Stockfleth, Alex Stratigos, Hisashi Uhara, Ricardo Vieira, Beate Volkmer, Martin A. Weinstock, Dagmar Whitaker, Iris Zalaudek, David C. Whiteman, Lieve Brochez

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Cancers of the skin are the most commonly occurring cancers in humans. In fair-skinned populations, up to 95% of keratinocyte skin cancers and 70–95% of cutaneous melanomas are caused by ultraviolet radiation and are thus theoretically preventable. Currently, however, there is no comprehensive global advice on practical steps to be taken to reduce the toll of skin cancer. To address this gap, an expert working group comprising clinicians and researchers from Africa, America, Asia, Australia, and Europe, together with learned societies (European Association of Dermato-Oncology, Euromelanoma, Euroskin, European Union of Medical Specialists, and the Melanoma World Society) reviewed the extant evidence and issued the following evidence-based recommendations for photoprotection as a strategy to prevent skin cancer. Fair skinned people, especially children, should minimise their exposure to ultraviolet radiation, and are advised to use protective measures when the UV index is forecast to reach 3 or higher. Protective measures include a combination of seeking shade, physical protection (e.g. clothing, hat, sunglasses), and applying broad-spectrum, SPF 30 + sunscreens to uncovered skin. Intentional exposure to solar ultraviolet radiation for the purpose of sunbathing and tanning is considered an unhealthy behaviour and should be avoided. Similarly, use of solaria and other artificial sources of ultraviolet radiation to encourage tanning should be strongly discouraged, through regulation if necessary. Primary prevention of skin cancer has a positive return on investment. We encourage policymakers to communicate these messages to the general public and promote their wider implementation.
Original languageEnglish
Article number114074
Number of pages5
JournalEuropean Journal of Cancer
Volume204
DOIs
Publication statusPublished - 1 Jun 2024

Keywords

  • Keratinocyte cancer
  • Melanoma
  • Prevention
  • Skin cancer
  • Ultraviolet radiation
  • UV-protection

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