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Skin Biopsy

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Over the past three decades, skin biopsy has gained widespread popularity as a widely used and safe procedure applied for quantifying intraepidermal nerve fibers. This procedure is utilized in diagnosing small fiber neuropathy. Skin biopsy holds potential for follow-up assessments as these nerve fibers regenerate. Additionally, dermal myelinated fibers can be investigated in inflammatory and hereditary polyneuropathies. Recent developments have also demonstrated the usefulness of skin biopsy in assessing biomarkers of neuropathic pain and protein deposits in neurodegenerative disorders.
Original languageEnglish
Title of host publicationEncyclopedia of the Neurological Sciences
EditorsJohn D. England
PublisherElsevier
PagesV4:847-V4:853
Volume4
Edition3
ISBN (Electronic)9780323957021
ISBN (Print)9780323957052
DOIs
Publication statusPublished - 1 Jan 2025

Keywords

  • Dermal nerve fibers
  • Diagnostic biomarkers
  • IENFD
  • Intraepidermal nerve fibers
  • Neuropathic pain
  • Nociception
  • Non-neuronal cells
  • Peripheral neuropathy
  • Skin biopsy
  • Small fiber neuropathy degeneration

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