Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation

Pieter A. Leermakers*, Anita E. M. Kneppers, Annemie M. W. J. Schols, Marco C. J. M. Kelders, Chiel C. de Theije, Lex B. Verdijk, Luc J. C. van Loon, Ramon C. J. Langen, Harry R. Gosker

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)769-778
Number of pages10
JournalMuscle & Nerve
Volume60
Issue number6
Early online date23 Oct 2019
DOIs
Publication statusPublished - Dec 2019

Keywords

  • inactivity
  • mitochondria
  • mitochondrial biogenesis
  • mitophagy
  • muscle unloading
  • skeletal muscle
  • LEG IMMOBILIZATION
  • OVER-EXPRESSION
  • SOLEUS MUSCLE
  • DYNAMICS
  • ATROPHY
  • FUNDC1
  • ACTIVATION
  • PATHWAYS
  • GENES
  • YOUNG

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