Site-specific prolongation of repolarization prevents postmyocardial infarction tachycardia

Ryan P. O'Hara; Veronique M.F. Meijborg; Pouya Jelvehgaran; Jeanne van der Waal; Gerard J.J. Boink; Natalia A. Trayanova; Ruben Coronel; Bastiaan J. Boukens

doi:10.1016/j.hroo.2023.06.003

Site-specific prolongation of repolarization prevents postmyocardial infarction tachycardia

Ryan P. O'Hara
, Veronique M.F. Meijborg
, Pouya Jelvehgaran
, Jeanne van der Waal
, Gerard J.J. Boink
, Natalia A. Trayanova
, Ruben Coronel
, Bastiaan J. Boukens^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Original language	English
Pages (from-to)	466-468
Number of pages	3
Journal	Heart Rhythm O2
Volume	4
Issue number	7
DOIs	https://doi.org/10.1016/j.hroo.2023.06.003
Publication status	Published - Jul 2023

Keywords

Antiarrhythmic therapy
Digital twin
Myocardial infarction
Reentry
Ventricular tachycardia

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10.1016/j.hroo.2023.06.003Licence: CC BY

Cite this

@article{93e5eb4859d442ca95226fc641df7dcb,

title = "Site-specific prolongation of repolarization prevents postmyocardial infarction tachycardia",

keywords = "Antiarrhythmic therapy, Digital twin, Myocardial infarction, Reentry, Ventricular tachycardia",

author = "O'Hara, \{Ryan P.\} and Meijborg, \{Veronique M.F.\} and Pouya Jelvehgaran and \{van der Waal\}, Jeanne and Boink, \{Gerard J.J.\} and Trayanova, \{Natalia A.\} and Ruben Coronel and Boukens, \{Bastiaan J.\}",

note = "Funding Information: This work was supported by the RHYTHM Leducq Grant (16CVD02) and GALANT (ZonMW) (116004202). Mr O{\textquoteright}Hara was supported by a National Science Foundation Graduate Research Fellowship ( DGE-1746891 ). Dr Boink was supported by European Research Council Starting Grant 714866 and associated proof-of-concept Grants 899422 and 101081921 ; Health Holland LentiPace II; Horizon 2020 Eurostars E114245 and E115484; and the Dutch Research Council Open Technology Program 18485. Funding Information: This work was supported by the RHYTHM Leducq Grant (16CVD02) and GALANT (ZonMW) (116004202). Mr O'Hara was supported by a National Science Foundation Graduate Research Fellowship (DGE-1746891). Dr Boink was supported by European Research Council Starting Grant 714866 and associated proof-of-concept Grants 899422 and 101081921; Health Holland LentiPace II; Horizon 2020 Eurostars E114245 and E115484; and the Dutch Research Council Open Technology Program 18485. The authors have no conflicts of interest to disclose. All authors attest they meet the current ICMJE criteria for authorship. All experiments were approved by the institutional review committee for experiments on animals, and animal handling was in accordance with the Dutch Law on Animal Experimentation and the European Directive for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (European Union Directive 86/609/EEC).",

year = "2023",

month = jul,

doi = "10.1016/j.hroo.2023.06.003",

language = "English",

volume = "4",

pages = "466--468",

journal = "Heart Rhythm O2",

issn = "2666-5018",

publisher = "Elsevier BV",

number = "7",

}

TY - JOUR

T1 - Site-specific prolongation of repolarization prevents postmyocardial infarction tachycardia

AU - O'Hara, Ryan P.

AU - Meijborg, Veronique M.F.

AU - Jelvehgaran, Pouya

AU - van der Waal, Jeanne

AU - Boink, Gerard J.J.

AU - Trayanova, Natalia A.

AU - Coronel, Ruben

AU - Boukens, Bastiaan J.

N1 - Funding Information: This work was supported by the RHYTHM Leducq Grant (16CVD02) and GALANT (ZonMW) (116004202). Mr O’Hara was supported by a National Science Foundation Graduate Research Fellowship ( DGE-1746891 ). Dr Boink was supported by European Research Council Starting Grant 714866 and associated proof-of-concept Grants 899422 and 101081921 ; Health Holland LentiPace II; Horizon 2020 Eurostars E114245 and E115484; and the Dutch Research Council Open Technology Program 18485. Funding Information: This work was supported by the RHYTHM Leducq Grant (16CVD02) and GALANT (ZonMW) (116004202). Mr O'Hara was supported by a National Science Foundation Graduate Research Fellowship (DGE-1746891). Dr Boink was supported by European Research Council Starting Grant 714866 and associated proof-of-concept Grants 899422 and 101081921; Health Holland LentiPace II; Horizon 2020 Eurostars E114245 and E115484; and the Dutch Research Council Open Technology Program 18485. The authors have no conflicts of interest to disclose. All authors attest they meet the current ICMJE criteria for authorship. All experiments were approved by the institutional review committee for experiments on animals, and animal handling was in accordance with the Dutch Law on Animal Experimentation and the European Directive for the Protection of Vertebrate Animals Used for Experimental and Other Scientific Purposes (European Union Directive 86/609/EEC).

PY - 2023/7

Y1 - 2023/7

KW - Antiarrhythmic therapy

KW - Digital twin

KW - Myocardial infarction

KW - Reentry

KW - Ventricular tachycardia

U2 - 10.1016/j.hroo.2023.06.003

DO - 10.1016/j.hroo.2023.06.003

M3 - Comment/Letter to the editor

C2 - 37520014

SN - 2666-5018

VL - 4

SP - 466

EP - 468

JO - Heart Rhythm O2

JF - Heart Rhythm O2

IS - 7

ER -