Single-case Design Studies in Children with Cerebral Palsy: A Scoping Review

Laura W. M. E. Beckers*, Rosalinde A. Stal, Rob J. E. M. Smeets, Patrick Onghena, Caroline H. G. Bastiaenen

*Corresponding author for this work

Research output: Contribution to journal(Systematic) Review article peer-review

Abstract

Aim: To critically evaluate single-case design (SCD) studies performed within the population of children/adolescents with cerebral palsy (CP). Methods: A scoping review of SCD studies of children/adolescents with CP. Demographic, methodological, and statistical data were extracted. Articles were evaluated using the Risk of Bias in N-of-1 Trials (RoBiNT) Scale and the Consolidated Standards of Reporting Trials (CONSORT) extension for N-of-1 trials (CENT 2015). Comments regarding strengths and limitations were analyzed. Results: Studies investigated the effects of a wide range of interventions on various outcomes. Most SCD types were adopted in multiple studies. All studies used visual inspection rather than visual analysis, often complemented with basic statistical descriptives. Risk of bias was high, particularly concerning internal validity. Many CENT items were insufficiently reported. Several benefits and limitations of SCD were identified. Conclusions: The quality of evidence from results of SCD studies needs to be increased through risk of bias reduction.

Original languageEnglish
Pages (from-to)73-105
Number of pages33
JournalDevelopmental Neurorehabilitation
Volume23
Issue number2
Early online date15 Aug 2019
DOIs
Publication statusPublished - 17 Feb 2020

Keywords

  • Single-case design
  • risk of bias
  • quality of reporting
  • cerebral palsy
  • review
  • INDUCED MOVEMENT THERAPY
  • VIRTUAL-REALITY
  • SUBJECT RESEARCH
  • UPPER-EXTREMITY
  • PHYSICAL-ACTIVITIES
  • N-OF-1 TRIALS
  • PERFORMANCE
  • BALANCE
  • REHABILITATION
  • INTERVENTION

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