TY - JOUR
T1 - Should We Still Focus That Much on Cardiovascular Mortality in End Stage Renal Disease Patients? The CONvective TRAnsport STudy
AU - den Hoedt, Claire H.
AU - Bots, Michiel L.
AU - Grooteman, Muriel P. C.
AU - Mazairac, Albert H. A.
AU - Penne, E. Lars
AU - van der Weerd, Neelke C.
AU - Ter Wee, Piet M.
AU - Nube, Menso J.
AU - Levesque, Renee
AU - Blankestijn, Peter J.
AU - van den Dorpel, Marinus A.
PY - 2013/4/19
Y1 - 2013/4/19
N2 - We studied the distribution of causes of death in the CONTRAST cohort and compared the proportion of cardiovascular deaths with other populations to answer the question whether cardiovascular mortality is still the principal cause of death in end stage renal disease. In addition, we compared patients who died from the three most common death causes. Finally, we aimed to study factors related to dialysis withdrawal.We used data from CONTRAST, a randomized controlled trial in 714 chronic hemodialysis patients comparing the effects of online hemodiafiltration versus low-flux hemodialysis. Causes of death were adjudicated. The distribution of causes of death was compared to that of the Dutch dialysis registry and of the Dutch general population.In CONTRAST, 231 patients died on treatment. 32% died from cardiovascular disease, 22% due to infection and 23% because of dialysis withdrawal. These proportions were similar to those in the Dutch dialysis registry and the proportional cardiovascular mortality was similar to that of the Dutch general population. cardiovascular death was more common in patients
AB - We studied the distribution of causes of death in the CONTRAST cohort and compared the proportion of cardiovascular deaths with other populations to answer the question whether cardiovascular mortality is still the principal cause of death in end stage renal disease. In addition, we compared patients who died from the three most common death causes. Finally, we aimed to study factors related to dialysis withdrawal.We used data from CONTRAST, a randomized controlled trial in 714 chronic hemodialysis patients comparing the effects of online hemodiafiltration versus low-flux hemodialysis. Causes of death were adjudicated. The distribution of causes of death was compared to that of the Dutch dialysis registry and of the Dutch general population.In CONTRAST, 231 patients died on treatment. 32% died from cardiovascular disease, 22% due to infection and 23% because of dialysis withdrawal. These proportions were similar to those in the Dutch dialysis registry and the proportional cardiovascular mortality was similar to that of the Dutch general population. cardiovascular death was more common in patients
U2 - 10.1371/journal.pone.0061155
DO - 10.1371/journal.pone.0061155
M3 - Article
C2 - 23620729
SN - 1932-6203
VL - 8
JO - PLOS ONE
JF - PLOS ONE
IS - 4
M1 - e61155
ER -