Abstract
Global obesity rates are increasing more and more. Short-chain fatty acids, the end products of fermentation of indigestible carbohydrates by intestinal bacteria, can influence metabolism and therefore play a role in the development of obesity and diabetes. The studies described in this dissertation show that the administration of short-chain fatty acids to the colon of overweight men increases energy expenditure and fat metabolism and reduces appetite and inflammation. The increase in the number of short-chain fatty acids in the colon by food intake can vitally contribute to the treatment or prevention of obesity and diabetes.
Original language | English |
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Award date | 23 Sept 2016 |
Place of Publication | Maastricht |
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Publication status | Published - 2016 |
Keywords
- obesity
- gut microbiota
- dietary fibers
- short-chain fatty acids
- human metabolism