Short- and Long-term exercise induced alterations in haemostasis: a review of the literature

Jelle J. Posthuma; Paola E. J. van der Meijden; Hugo ten Cate; Henri M. H. Spronk

doi:10.1016/j.blre.2014.10.005

Short- and Long-term exercise induced alterations in haemostasis: a review of the literature

Jelle J. Posthuma^*, Paola E. J. van der Meijden, Hugo ten Cate, Henri M. H. Spronk

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Although regular exercise is beneficial for health, exercise-related thrombotic events, such as venous thromboembolism and myocardial infarctions, are occasionally observed. These events are characterized by a prothrombotic condition in which interactions between coagulation factors, the vessel wall and the fibrinolytic system play an important role. Apparently, various durations and intensities of exercise have different effects on haemostasis and especially high intensity exercise tends to increase the risk of thrombotic events. However, the mechanisms behind this have not been entirely established. In this review we provide an overview of the various effects of the different intensities and durations of exercise on haemostasis. Overall, the haemostatic profile is mainly affected by the intensity of exercise; and is more pronounced after high (>80%) compared to low intensity (

Original language	English
Pages (from-to)	171-178
Journal	Blood Reviews
Volume	29
Issue number	3
DOIs	https://doi.org/10.1016/j.blre.2014.10.005
Publication status	Published - May 2015

Keywords

Exercise
Haemostasis
Platelets
Cardiovascular diseases
Blood coagulation

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10.1016/j.blre.2014.10.005

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title = "Short- and Long-term exercise induced alterations in haemostasis: a review of the literature",

abstract = "Although regular exercise is beneficial for health, exercise-related thrombotic events, such as venous thromboembolism and myocardial infarctions, are occasionally observed. These events are characterized by a prothrombotic condition in which interactions between coagulation factors, the vessel wall and the fibrinolytic system play an important role. Apparently, various durations and intensities of exercise have different effects on haemostasis and especially high intensity exercise tends to increase the risk of thrombotic events. However, the mechanisms behind this have not been entirely established. In this review we provide an overview of the various effects of the different intensities and durations of exercise on haemostasis. Overall, the haemostatic profile is mainly affected by the intensity of exercise; and is more pronounced after high (>80%) compared to low intensity (",

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T1 - Short- and Long-term exercise induced alterations in haemostasis: a review of the literature

AU - Posthuma, Jelle J.

AU - van der Meijden, Paola E. J.

AU - ten Cate, Hugo

AU - Spronk, Henri M. H.

PY - 2015/5

Y1 - 2015/5

N2 - Although regular exercise is beneficial for health, exercise-related thrombotic events, such as venous thromboembolism and myocardial infarctions, are occasionally observed. These events are characterized by a prothrombotic condition in which interactions between coagulation factors, the vessel wall and the fibrinolytic system play an important role. Apparently, various durations and intensities of exercise have different effects on haemostasis and especially high intensity exercise tends to increase the risk of thrombotic events. However, the mechanisms behind this have not been entirely established. In this review we provide an overview of the various effects of the different intensities and durations of exercise on haemostasis. Overall, the haemostatic profile is mainly affected by the intensity of exercise; and is more pronounced after high (>80%) compared to low intensity (

AB - Although regular exercise is beneficial for health, exercise-related thrombotic events, such as venous thromboembolism and myocardial infarctions, are occasionally observed. These events are characterized by a prothrombotic condition in which interactions between coagulation factors, the vessel wall and the fibrinolytic system play an important role. Apparently, various durations and intensities of exercise have different effects on haemostasis and especially high intensity exercise tends to increase the risk of thrombotic events. However, the mechanisms behind this have not been entirely established. In this review we provide an overview of the various effects of the different intensities and durations of exercise on haemostasis. Overall, the haemostatic profile is mainly affected by the intensity of exercise; and is more pronounced after high (>80%) compared to low intensity (

KW - Exercise

KW - Haemostasis

KW - Platelets

KW - Cardiovascular diseases

KW - Blood coagulation

U2 - 10.1016/j.blre.2014.10.005

DO - 10.1016/j.blre.2014.10.005

M3 - Article

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SN - 0268-960X

VL - 29

SP - 171

EP - 178

JO - Blood Reviews

JF - Blood Reviews

IS - 3

ER -

Short- and Long-term exercise induced alterations in haemostasis: a review of the literature

Abstract

Keywords

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