Sex and Common Germline Variants Affect the Toxicity Profile and Pharmacokinetics of Alectinib: A Nationwide Cohort Study in Patients With ALK-Positive NSCLC

Niels Heersche, Daan A C Lanser, M Benthe Muntinghe-Wagenaar, Ma Ida Mohmaed Ali, Ezgi B Ulas, Tessa M A Trooster, Evert de Jonge, Esther Oomen-de Hoop, Marthe S Paats, Idris Bahce, Sander Croes, Lizza E L Hendriks, Anthonie J van der Wekken, Anne-Marie C Dingemans, Alwin D R Huitema, Ron H N van Schaik, Ron H J Mathijssen*, G D Marijn Veerman

*Corresponding author for this work

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Pharmacology, Toxicology and Pharmaceutical Science