Abstract
Levetiracetam may induce serious behavioral disturbances, especially after surgical resection of frontal lobe low-grade glioma. Two patients, treated with levetiracetam, developed serious psychiatric complications postoperatively which completely resolved after switching to valproate. We aim to create awareness for this serious but reversible adverse effect of levetiracetam in this specific patient category.
Original language | English |
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Pages (from-to) | 471-473 |
Number of pages | 3 |
Journal | British Journal of Neurosurgery |
Volume | 31 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2017 |
Keywords
- Low-grade glioma
- frontal lobe resection
- levetiracetam
- valproate
- psychiatric symptoms
- behavioral changes
- METAANALYSIS
- EPILEPSY
- PROFILE