@article{f53ec79fc1194775a9b2bf4ac439cf23,
title = "Selenium-Modified Microgels as Bio-Inspired Oxidation Catalysts",
abstract = "Active colloidal catalysts inspired by glutathione peroxidase (GPx) were synthesized by integration of catalytically active selenium (Se) moieties into aqueous microgels. A diselenide crosslinker (Se X-linker) was successfully synthesized and incorporated into microgels through precipitation polymerization, along with the conventional crosslinker N,N'-methylenebis(acrylamide) (BIS). Diselenide bonds within the microgels were cleaved through oxidation by H2O2 and converted to seleninic acid whilst maintaining the intact microgel microstructure. Through this approach catalytically active microgels with variable amounts of seleninic acid were synthesized. Remarkably, the microgels exhibited higher catalytic activity and selectivity at low reaction temperatures than the molecular Se catalyst in a model oxidation reaction of acrolein to acrylic acid and methyl acrylate.",
keywords = "adsorption, aerobic oxidation, aldehydes, emulsions, glutathione-peroxidase, hydration, microgels, nanogels, organocatalysis, polymers, redox chemistry, release, selenium, size modulation, POLYMERS, GLUTATHIONE-PEROXIDASE, ALDEHYDES, RELEASE, ADSORPTION, HYDRATION, SIZE MODULATION, AEROBIC OXIDATION, NANOGELS, EMULSIONS",
author = "K.H. Tan and W.J. Xu and S. Stefka and D.E. Demco and T. Kharandiuk and V. Ivasiv and R. Nebesnyi and V.S. Petrovskii and I.I. Potemkin and A. Pich",
note = "Funding Information: We acknowledge the Volkswagen Stiftung for funding the project A115859. We thank SFB 985 “Functional Microgels and Microgel Systems” for financial support. The financial support of the Government of Russian Federation within Act 211, Contract 02.A03.21.0011, and the Russian Foundation for Basic Research, project No. 19-03-00472, is gratefully acknowledged. The computer simulations were carried out using the equipment of the shared research facilities of HPC computing resources at Lomonosov Moscow State University. We also thank Dr. Walter Tillmann for the FTIR and Raman spectroscopy measurements and Lindsey Weger for proofreading the manuscript. Thanks go to Anna Holzberger for the German translation. Funding Information: We acknowledge the Volkswagen Stiftung for funding the project A115859. We thank SFB 985 ?Functional Microgels and Microgel Systems? for financial support. The financial support of the Government of Russian Federation within Act 211, Contract 02.A03.21.0011, and the Russian Foundation for Basic Research, project No. 19-03-00472, is gratefully acknowledged. The computer simulations were carried out using the equipment of the shared research facilities of HPC computing resources at Lomonosov Moscow State University. We also thank Dr. Walter Tillmann for the FTIR and Raman spectroscopy measurements and Lindsey Weger for proofreading the manuscript. Thanks go to Anna Holzberger for the German translation. Publisher Copyright: {\textcopyright} 2019 Wiley-VCH Verlag GmbH \& Co. KGaA, Weinheim",
year = "2019",
month = jul,
day = "15",
doi = "10.1002/anie.201901161",
language = "English",
volume = "58",
pages = "9791--9796",
journal = "Angewandte Chemie-International Edition",
issn = "1433-7851",
publisher = "John Wiley \& Sons Inc.",
number = "29",
}