Selective NADH communication from alpha-ketoglutarate dehydrogenase to mitochondrial transhydrogenase prevents reactive oxygen species formation under reducing conditions in the heart

Michael Wagner, Edoardo Bertero, Alexander Nickel, Michael Kohlhaas, Gary E. Gibson, Ward Heggermont, Stephane Heymans, Christoph Maack*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number53
Number of pages16
JournalBasic Research in Cardiology
Volume115
Issue number5
DOIs
Publication statusPublished - 3 Aug 2020

Keywords

  • Mitochondria
  • alpha-Ketoglutarate dehydrogenase
  • Reactive oxygen species
  • Nicotinamide nucleotide transhydrogenase
  • CA2+ UPTAKE
  • COMPLEX
  • CATALASE
  • TARGET
  • PEROXIDE
  • RELEASE
  • OXIDASE
  • ENZYME

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