Second transplants for multiple myeloma relapsing after a previous autotransplant-reduced-intensity allogeneic vs autologous transplantation

C. O. Freytes; D. H. Vesole; J. LeRademacher; X. Zhong; R. P. Gale; R. A. Kyle; D. E. Reece; J. Gibson; H. C. Schouten; P. L. McCarthy; S. Lonial; A. Y. Krishnan; A. Dispenzieri; P. N. Hari

doi:10.1038/bmt.2013.187

Second transplants for multiple myeloma relapsing after a previous autotransplant-reduced-intensity allogeneic vs autologous transplantation

C. O. Freytes, D. H. Vesole, J. LeRademacher, X. Zhong, R. P. Gale, R. A. Kyle, D. E. Reece, J. Gibson, H. C. Schouten, P. L. McCarthy, S. Lonial, A. Y. Krishnan, A. Dispenzieri, P. N. Hari^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

There is no standard therapy for multiple myeloma relapsing after an autotransplant. We compared the outcomes of a second autotransplant (N=137) with those of an allotransplant (N=152) after non-myeloablative or reduced-intensity conditioning (NST/RIC) in 289 subjects reported to the CIBMTR from 1995 to 2008. NST/RIC recipients were younger (median age 53 vs 56 years; P

Original language	English
Pages (from-to)	416-421
Journal	Bone Marrow Transplantation
Volume	49
Issue number	3
DOIs	https://doi.org/10.1038/bmt.2013.187
Publication status	Published - Mar 2014

Keywords

multiple myeloma
allogeneic
salvage transplant

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Cite this

Freytes, C. O., Vesole, D. H., LeRademacher, J., Zhong, X., Gale, R. P., Kyle, R. A., Reece, D. E., Gibson, J., Schouten, H. C., McCarthy, P. L., Lonial, S., Krishnan, A. Y., Dispenzieri, A., & Hari, P. N. (2014). Second transplants for multiple myeloma relapsing after a previous autotransplant-reduced-intensity allogeneic vs autologous transplantation. Bone Marrow Transplantation, 49(3), 416-421. https://doi.org/10.1038/bmt.2013.187

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abstract = "There is no standard therapy for multiple myeloma relapsing after an autotransplant. We compared the outcomes of a second autotransplant (N=137) with those of an allotransplant (N=152) after non-myeloablative or reduced-intensity conditioning (NST/RIC) in 289 subjects reported to the CIBMTR from 1995 to 2008. NST/RIC recipients were younger (median age 53 vs 56 years; P",

keywords = "multiple myeloma, allogeneic, salvage transplant",

author = "Freytes, {C. O.} and Vesole, {D. H.} and J. LeRademacher and X. Zhong and Gale, {R. P.} and Kyle, {R. A.} and Reece, {D. E.} and J. Gibson and Schouten, {H. C.} and McCarthy, {P. L.} and S. Lonial and Krishnan, {A. Y.} and A. Dispenzieri and Hari, {P. N.}",

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Freytes, CO, Vesole, DH, LeRademacher, J, Zhong, X, Gale, RP, Kyle, RA, Reece, DE, Gibson, J, Schouten, HC, McCarthy, PL, Lonial, S, Krishnan, AY, Dispenzieri, A & Hari, PN 2014, 'Second transplants for multiple myeloma relapsing after a previous autotransplant-reduced-intensity allogeneic vs autologous transplantation', Bone Marrow Transplantation, vol. 49, no. 3, pp. 416-421. https://doi.org/10.1038/bmt.2013.187

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AU - Freytes, C. O.

AU - Vesole, D. H.

AU - LeRademacher, J.

AU - Zhong, X.

AU - Gale, R. P.

AU - Kyle, R. A.

AU - Reece, D. E.

AU - Gibson, J.

AU - Schouten, H. C.

AU - McCarthy, P. L.

AU - Lonial, S.

AU - Krishnan, A. Y.

AU - Dispenzieri, A.

AU - Hari, P. N.

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AB - There is no standard therapy for multiple myeloma relapsing after an autotransplant. We compared the outcomes of a second autotransplant (N=137) with those of an allotransplant (N=152) after non-myeloablative or reduced-intensity conditioning (NST/RIC) in 289 subjects reported to the CIBMTR from 1995 to 2008. NST/RIC recipients were younger (median age 53 vs 56 years; P

KW - multiple myeloma

KW - allogeneic

KW - salvage transplant

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