Scoring Systems for Immunohistochemistry in Urothelial Carcinoma

Mark Sebastian Bösherz*, Iryna V. Samarska, Nadine T. Gaisa

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Immunohistochemistry is widely used in diagnostic and scientific analysis of urothelial carcinoma. Objective interpretation of staining results is mandatory for accuracy and comparability in diagnostic and therapeutic patient care as well as research. Herein we summarize and explain standardized microscopic evaluation and scoring approaches for immunohistochemical stainings. We focus on commonly used and generally feasible approaches for different cellular compartments and comment on their utility in diagnostics and research practice.
Original languageEnglish
Title of host publicationUrothelial Carcinoma
PublisherHumana Press
Pages3-25
Number of pages23
Volume2684
DOIs
Publication statusPublished - 1 Jan 2023

Publication series

SeriesMethods in Molecular Biology
Volume2684
ISSN1064-3745

Keywords

  • Immunohistochemistry
  • Scoring
  • Therapeutic markers
  • Tumor markers
  • Urothelial carcinoma

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