TY - JOUR
T1 - Sarcopenia
T2 - revised European consensus on definition and diagnosis
AU - Cruz-Jentoft, Alfonso J.
AU - Bahat, Gulistan
AU - Bauer, Juergen
AU - Boirie, Yves
AU - Bruyere, Olivier
AU - Cederholm, Tommy
AU - Cooper, Cyrus
AU - Landi, Francesco
AU - Rolland, Yves
AU - Sayer, Avan Aihie
AU - Schneider, Stephane M.
AU - Sieber, Cornel C.
AU - Topinkova, Eva
AU - Vandewoude, Maurits
AU - Visser, Marjolein
AU - Zamboni, Mauro
AU - Writing Group European Working Group
AU - Extended Group EWGSOP2
AU - Schols, Jos
PY - 2019/7
Y1 - 2019/7
N2 - Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings.Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia.Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia.Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.
AB - Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings.Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia.Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia.Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.
KW - sarcopenia
KW - muscle strength
KW - physical performance
KW - muscle assessment
KW - EWGSOP2
KW - older people
KW - SKELETAL-MUSCLE MASS
KW - BIOELECTRICAL-IMPEDANCE ANALYSIS
KW - OF-LIFE QUESTIONNAIRE
KW - LOWER-EXTREMITY FUNCTION
KW - ADIPOSE-TISSUE VOLUMES
KW - DWELLING OLDER-PEOPLE
KW - ALL-CAUSE MORTALITY
KW - COMPUTED-TOMOGRAPHY
KW - GRIP STRENGTH
KW - GAIT SPEED
U2 - 10.1093/ageing/afz046
DO - 10.1093/ageing/afz046
M3 - Erratum / corrigendum / retractions
C2 - 31081853
SN - 0002-0729
VL - 48
SP - 601
JO - Age and Ageing
JF - Age and Ageing
IS - 4
ER -