Sarcopenia in Advanced COPD Affects Cardiometabolic Risk Reduction by Short-Term High-intensity Pulmonary Rehabilitation

Narca Cebron Lipovec; Annemie M. W. J. Schols; Bram van den Borst; Rosanne J. H. C. G. Beijers; Tatjana Kosten; Daniel Omersa; Mitja Lainscak

doi:10.1016/j.jamda.2016.05.002

Sarcopenia in Advanced COPD Affects Cardiometabolic Risk Reduction by Short-Term High-intensity Pulmonary Rehabilitation

Narca Cebron Lipovec, Annemie M. W. J. Schols, Bram van den Borst, Rosanne J. H. C. G. Beijers, Tatjana Kosten, Daniel Omersa, Mitja Lainscak^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Web of Science)

Abstract

Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index

Original language	English
Pages (from-to)	814-820
Journal	Journal of the American Medical Directors Association
Volume	17
Issue number	9
DOIs	https://doi.org/10.1016/j.jamda.2016.05.002
Publication status	Published - 1 Sep 2016

Keywords

COPD
sarcopenia
cardiometabolic risk
pulmonary rehabilitation

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10.1016/j.jamda.2016.05.002

Cite this

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title = "Sarcopenia in Advanced COPD Affects Cardiometabolic Risk Reduction by Short-Term High-intensity Pulmonary Rehabilitation",

abstract = "Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index ",

keywords = "COPD, sarcopenia, cardiometabolic risk, pulmonary rehabilitation",

author = "{Cebron Lipovec}, Narca and Schols, {Annemie M. W. J.} and {van den Borst}, Bram and Beijers, {Rosanne J. H. C. G.} and Tatjana Kosten and Daniel Omersa and Mitja Lainscak",

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Sarcopenia in Advanced COPD Affects Cardiometabolic Risk Reduction by Short-Term High-intensity Pulmonary Rehabilitation. / Cebron Lipovec, Narca; Schols, Annemie M. W. J.; van den Borst, Bram et al.

In: Journal of the American Medical Directors Association, Vol. 17, No. 9, 01.09.2016, p. 814-820.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

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AU - Cebron Lipovec, Narca

AU - Schols, Annemie M. W. J.

AU - van den Borst, Bram

AU - Beijers, Rosanne J. H. C. G.

AU - Kosten, Tatjana

AU - Omersa, Daniel

AU - Lainscak, Mitja

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N2 - Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index

AB - Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index

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