TY - JOUR
T1 - Sarcopenia in Advanced COPD Affects Cardiometabolic Risk Reduction by Short-Term High-intensity Pulmonary Rehabilitation
AU - Cebron Lipovec, Narca
AU - Schols, Annemie M. W. J.
AU - van den Borst, Bram
AU - Beijers, Rosanne J. H. C. G.
AU - Kosten, Tatjana
AU - Omersa, Daniel
AU - Lainscak, Mitja
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index
AB - Objectives: Sarcopenia is common in chronic obstructive pulmonary disease (COPD) and may contribute to increased cardiometabolic risk. Interventions to reduce cardiometabolic risk in advanced COPD have been scarcely studied. We have investigated the cardiometabolic effect of a short-term high-intensity rehabilitation program in sarcopenic and nonsarcopenic patients with advanced COPD. Design: Prospective observational study. Setting: Inpatient 4-week short-term high-intensity pulmonary rehabilitation program at the University Clinic Golnik, Slovenia. Participants: 112 stable COPD patients (66 +/- 8 years, 85% GOLD III/IV, 66% men). Measurements: Blood biomarkers were assessed at baseline and after rehabilitation. Sarcopenia was assessed at baseline (skeletal muscle index
KW - COPD
KW - sarcopenia
KW - cardiometabolic risk
KW - pulmonary rehabilitation
U2 - 10.1016/j.jamda.2016.05.002
DO - 10.1016/j.jamda.2016.05.002
M3 - Article
C2 - 27321867
SN - 1525-8610
VL - 17
SP - 814
EP - 820
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
IS - 9
ER -