TY - JOUR
T1 - Same-day discharge after laparoscopic hysterectomy for benign/premalignant disease
T2 - A multicentre randomised controlled trial
AU - Dedden, Suzanne J.
AU - Maas, Jacques W. M.
AU - Smeets, Nicol A. C.
AU - van Hamont, Dennis
AU - Groenman, Freek A.
AU - Lim, Arianne C.
AU - van Vliet, Huib A. A. M.
AU - van Der Steeg, Jan Willem
AU - Leemans, Jaklien C.
AU - Meijer, Patrick
AU - van Kuijk, Sander M. J.
AU - Huirne, Judith A. F.
AU - Bongers, Marlies Y.
AU - Geomini, Peggy M. A. J.
PY - 2024/7/1
Y1 - 2024/7/1
N2 - ObjectiveTo evaluate whether physical function and quality of life was influenced by discharge on the same-day after a total laparoscopic hysterectomy.DesignMulticentre non-inferiority randomised controlled trial.SettingFive teaching hospitals and two university hospitals in the Netherlands.PopulationPatients undergoing laparoscopic hysterectomy for benign or premalignant disease.MethodsFollowing informed consent, participants were allocated 1:1 either to same-day discharge (SDD) or next-day discharge (NDD).Main Outcome MeasuresThe primary outcome was physical function at 7 days after surgery measured by the Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function short Form 10A. Secondary outcomes were physical function and quality of life at 1 and 3 days and 6 weeks after surgery measured with PROMIS short Form 10A and the EuroQol questionnaire (EQ-5D-5L).ResultsTwo hundred and five patients were included of whom 105 were allocated to SDD and 100 to NDD. Physical function 7 days after surgery was 35.95 in the SDD group and 35.63 in the control group (mean difference 0.32; 95% CI [0.07-0.57]). As the upper limit of the 95% CI does not exceed the non-inferiority margin of 4 points, non-inferiority of SDD could be demonstrated. No difference in physical function nor quality of life on Days 1 and 3 and 6 weeks could be found.ConclusionThis research demonstrates same-day discharge after laparoscopic hysterectomy is non-inferior to next day discharge in physical function 7 days after surgery.
AB - ObjectiveTo evaluate whether physical function and quality of life was influenced by discharge on the same-day after a total laparoscopic hysterectomy.DesignMulticentre non-inferiority randomised controlled trial.SettingFive teaching hospitals and two university hospitals in the Netherlands.PopulationPatients undergoing laparoscopic hysterectomy for benign or premalignant disease.MethodsFollowing informed consent, participants were allocated 1:1 either to same-day discharge (SDD) or next-day discharge (NDD).Main Outcome MeasuresThe primary outcome was physical function at 7 days after surgery measured by the Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function short Form 10A. Secondary outcomes were physical function and quality of life at 1 and 3 days and 6 weeks after surgery measured with PROMIS short Form 10A and the EuroQol questionnaire (EQ-5D-5L).ResultsTwo hundred and five patients were included of whom 105 were allocated to SDD and 100 to NDD. Physical function 7 days after surgery was 35.95 in the SDD group and 35.63 in the control group (mean difference 0.32; 95% CI [0.07-0.57]). As the upper limit of the 95% CI does not exceed the non-inferiority margin of 4 points, non-inferiority of SDD could be demonstrated. No difference in physical function nor quality of life on Days 1 and 3 and 6 weeks could be found.ConclusionThis research demonstrates same-day discharge after laparoscopic hysterectomy is non-inferior to next day discharge in physical function 7 days after surgery.
KW - laparoscopic hysterectomy
KW - same-day discharge
KW - SURGERY
U2 - 10.1111/1471-0528.17911
DO - 10.1111/1471-0528.17911
M3 - Article
SN - 1470-0328
JO - Bjog-an International Journal of Obstetrics and Gynaecology
JF - Bjog-an International Journal of Obstetrics and Gynaecology
ER -