Safety and efficacy of tubal flushing with ethiodized oil

Inez Roest

Research output: ThesisDoctoral ThesisExternal prepared

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On average, one out of every six couples consults a doctor, because they did not get pregnant after trying for at least one year. One of the investigations that can be performed during the fertility workup in subfertile women is tubal patency testing. Previous research has shown that the use of an oil-based liquid (ethiodized oil) during this diagnostic procedure leads to 10% more pregnancies, compared to the use of a water-based liquid. However, the mechanism behind this fertility enhancing effect of ethiodized oil remains unclear after more than 50 years of speculations. This thesis investigated the safety of ethiodized oil during tubal patency testing. Furthermore, it discussed the fertility-enhancing effect of ethiodized oil and its implementation in different methods of tubal testing.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
  • Bongers, Marlies, Supervisor
  • Mijatovic, V., Supervisor, External person
  • Mol, B. W. J., Co-Supervisor, External person
  • Koks, C.A.M., Co-Supervisor, External person
Award date5 Apr 2023
Place of PublicationMaastricht
Print ISBNs9789464219890
Publication statusPublished - 2023


  • subfertility
  • tubal testing
  • ethiodized oil
  • safety


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