Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida.

S.M. Lansen-Koch, B. Govaert, D. Oerlemans, J. Melenhorst, J.S.H. Vles, E. Cornips, E.H.J. Weil, L.W.E. van Heurn, C.G.M.I. Baeten, W.G. van Gemert

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Abstract

Aim: Sacral nerve modulation is a well accepted method for the treatment of defaecation disorders and voiding dysfunction. Results of sacral nerve modulation in patients with spinal cord lesions are not well assessed, but preliminary results look poor. Therefore, the purpose of this study was to assess the effectiveness of sacral nerve modulation for defaecation disorders and voiding dysfunction in patients with spina bifida. Method: Consecutive patients with spina bifida suffering from a myelomeningocele and combined faecal and urinary functional disorders that were eligible for peripheral nerve evaluation were studied. A permanent sacral nerve modulation implantation was performed after successful peripheral nerve evaluation (PNE). Results: Ten patients (four females) were included in this study with a median age of 26.4 (range 11.1-41.0) years. In two the PNE was not possible. The median faecal incontinence days (6.0 vs. 3.5) and episodes (8.5 vs. 3.5) per 21 days decreased significantly during the 3 week period of PNE (p=0.033). Only 3/10 (30%) patients had a more than 50% improvement and proceeded to a permanent sacral nerve modulation implantation. In one patient it was not possible to perform the permanent implant. Conclusions: Preliminary results of sacral nerve modulation in a subgroup of spina bifida patients with combined faecal and urinary functional disorders look promising, but long-term results in larger patient groups need to be studied.
Original languageEnglish
Pages (from-to)508-514
JournalColorectal Disease
Volume14
Issue number4
DOIs
Publication statusPublished - 1 Jan 2012

Cite this

Lansen-Koch, S.M. ; Govaert, B. ; Oerlemans, D. ; Melenhorst, J. ; Vles, J.S.H. ; Cornips, E. ; Weil, E.H.J. ; van Heurn, L.W.E. ; Baeten, C.G.M.I. ; van Gemert, W.G. / Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida. In: Colorectal Disease. 2012 ; Vol. 14, No. 4. pp. 508-514.
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title = "Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida.",
abstract = "Aim: Sacral nerve modulation is a well accepted method for the treatment of defaecation disorders and voiding dysfunction. Results of sacral nerve modulation in patients with spinal cord lesions are not well assessed, but preliminary results look poor. Therefore, the purpose of this study was to assess the effectiveness of sacral nerve modulation for defaecation disorders and voiding dysfunction in patients with spina bifida. Method: Consecutive patients with spina bifida suffering from a myelomeningocele and combined faecal and urinary functional disorders that were eligible for peripheral nerve evaluation were studied. A permanent sacral nerve modulation implantation was performed after successful peripheral nerve evaluation (PNE). Results: Ten patients (four females) were included in this study with a median age of 26.4 (range 11.1-41.0) years. In two the PNE was not possible. The median faecal incontinence days (6.0 vs. 3.5) and episodes (8.5 vs. 3.5) per 21 days decreased significantly during the 3 week period of PNE (p=0.033). Only 3/10 (30{\%}) patients had a more than 50{\%} improvement and proceeded to a permanent sacral nerve modulation implantation. In one patient it was not possible to perform the permanent implant. Conclusions: Preliminary results of sacral nerve modulation in a subgroup of spina bifida patients with combined faecal and urinary functional disorders look promising, but long-term results in larger patient groups need to be studied.",
author = "S.M. Lansen-Koch and B. Govaert and D. Oerlemans and J. Melenhorst and J.S.H. Vles and E. Cornips and E.H.J. Weil and {van Heurn}, L.W.E. and C.G.M.I. Baeten and {van Gemert}, W.G.",
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pages = "508--514",
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Lansen-Koch, SM, Govaert, B, Oerlemans, D, Melenhorst, J, Vles, JSH, Cornips, E, Weil, EHJ, van Heurn, LWE, Baeten, CGMI & van Gemert, WG 2012, 'Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida.', Colorectal Disease, vol. 14, no. 4, pp. 508-514. https://doi.org/10.1111/j.1463-1318.2011.02678.x

Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida. / Lansen-Koch, S.M.; Govaert, B.; Oerlemans, D.; Melenhorst, J.; Vles, J.S.H.; Cornips, E.; Weil, E.H.J.; van Heurn, L.W.E.; Baeten, C.G.M.I.; van Gemert, W.G.

In: Colorectal Disease, Vol. 14, No. 4, 01.01.2012, p. 508-514.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida.

AU - Lansen-Koch, S.M.

AU - Govaert, B.

AU - Oerlemans, D.

AU - Melenhorst, J.

AU - Vles, J.S.H.

AU - Cornips, E.

AU - Weil, E.H.J.

AU - van Heurn, L.W.E.

AU - Baeten, C.G.M.I.

AU - van Gemert, W.G.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - Aim: Sacral nerve modulation is a well accepted method for the treatment of defaecation disorders and voiding dysfunction. Results of sacral nerve modulation in patients with spinal cord lesions are not well assessed, but preliminary results look poor. Therefore, the purpose of this study was to assess the effectiveness of sacral nerve modulation for defaecation disorders and voiding dysfunction in patients with spina bifida. Method: Consecutive patients with spina bifida suffering from a myelomeningocele and combined faecal and urinary functional disorders that were eligible for peripheral nerve evaluation were studied. A permanent sacral nerve modulation implantation was performed after successful peripheral nerve evaluation (PNE). Results: Ten patients (four females) were included in this study with a median age of 26.4 (range 11.1-41.0) years. In two the PNE was not possible. The median faecal incontinence days (6.0 vs. 3.5) and episodes (8.5 vs. 3.5) per 21 days decreased significantly during the 3 week period of PNE (p=0.033). Only 3/10 (30%) patients had a more than 50% improvement and proceeded to a permanent sacral nerve modulation implantation. In one patient it was not possible to perform the permanent implant. Conclusions: Preliminary results of sacral nerve modulation in a subgroup of spina bifida patients with combined faecal and urinary functional disorders look promising, but long-term results in larger patient groups need to be studied.

AB - Aim: Sacral nerve modulation is a well accepted method for the treatment of defaecation disorders and voiding dysfunction. Results of sacral nerve modulation in patients with spinal cord lesions are not well assessed, but preliminary results look poor. Therefore, the purpose of this study was to assess the effectiveness of sacral nerve modulation for defaecation disorders and voiding dysfunction in patients with spina bifida. Method: Consecutive patients with spina bifida suffering from a myelomeningocele and combined faecal and urinary functional disorders that were eligible for peripheral nerve evaluation were studied. A permanent sacral nerve modulation implantation was performed after successful peripheral nerve evaluation (PNE). Results: Ten patients (four females) were included in this study with a median age of 26.4 (range 11.1-41.0) years. In two the PNE was not possible. The median faecal incontinence days (6.0 vs. 3.5) and episodes (8.5 vs. 3.5) per 21 days decreased significantly during the 3 week period of PNE (p=0.033). Only 3/10 (30%) patients had a more than 50% improvement and proceeded to a permanent sacral nerve modulation implantation. In one patient it was not possible to perform the permanent implant. Conclusions: Preliminary results of sacral nerve modulation in a subgroup of spina bifida patients with combined faecal and urinary functional disorders look promising, but long-term results in larger patient groups need to be studied.

U2 - 10.1111/j.1463-1318.2011.02678.x

DO - 10.1111/j.1463-1318.2011.02678.x

M3 - Article

VL - 14

SP - 508

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JO - Colorectal Disease

JF - Colorectal Disease

SN - 1462-8910

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Lansen-Koch SM, Govaert B, Oerlemans D, Melenhorst J, Vles JSH, Cornips E et al. Sacral nerve modulation for defaecation and micturition disorders in patients with spina bifida. Colorectal Disease. 2012 Jan 1;14(4):508-514. https://doi.org/10.1111/j.1463-1318.2011.02678.x