Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Mireille M. J. P. E. Sthijns*, Paul M. Schiffers, Ger M. Janssen, Kristien J. A. Lemmens, Bart Ides, Philippe Vangrieken, Freek G. Bouwman, Edwin C. Mariman, Irina Pader, Elias S. J. Arner, Katarina Johansson, Aalt Bast, Guido R. M. M. Haenen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1177-1189
Number of pages13
JournalBiochimica et Biophysica Acta-general Subjects
Volume1861
Issue number5
DOIs
Publication statusPublished - May 2017

Keywords

  • Rutin
  • Flavonoids
  • Nrf2
  • Adaptation
  • Endothelial function
  • NF-KAPPA-B
  • DIETARY FLAVONOID QUERCETIN
  • REACTIVE OXYGEN
  • FLAVANOL (-)-EPICATECHIN
  • FLUORESCENT-PROBES
  • MEDIATED DILATION
  • DYSFUNCTION
  • GLUTATHIONE
  • NRF2
  • PATHWAY

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