Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

Mireille M. J. P. E. Sthijns*, Paul M. Schiffers, Ger M. Janssen, Kristien J. A. Lemmens, Bart Ides, Philippe Vangrieken, Freek G. Bouwman, Edwin C. Mariman, Irina Pader, Elias S. J. Arner, Katarina Johansson, Aalt Bast, Guido R. M. M. Haenen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1177-1189
Number of pages13
JournalBiochimica et Biophysica Acta-general Subjects
Volume1861
Issue number5
DOIs
Publication statusPublished - May 2017

Keywords

  • Rutin
  • Flavonoids
  • Nrf2
  • Adaptation
  • Endothelial function
  • NF-KAPPA-B
  • DIETARY FLAVONOID QUERCETIN
  • REACTIVE OXYGEN
  • FLAVANOL (-)-EPICATECHIN
  • FLUORESCENT-PROBES
  • MEDIATED DILATION
  • DYSFUNCTION
  • GLUTATHIONE
  • NRF2
  • PATHWAY

Cite this

@article{c7418c7ea3cd47c6bf1826a7b03325c7,
title = "Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress",
keywords = "Rutin, Flavonoids, Nrf2, Adaptation, Endothelial function, NF-KAPPA-B, DIETARY FLAVONOID QUERCETIN, REACTIVE OXYGEN, FLAVANOL (-)-EPICATECHIN, FLUORESCENT-PROBES, MEDIATED DILATION, DYSFUNCTION, GLUTATHIONE, NRF2, PATHWAY",
author = "Sthijns, {Mireille M. J. P. E.} and Schiffers, {Paul M.} and Janssen, {Ger M.} and Lemmens, {Kristien J. A.} and Bart Ides and Philippe Vangrieken and Bouwman, {Freek G.} and Mariman, {Edwin C.} and Irina Pader and Arner, {Elias S. J.} and Katarina Johansson and Aalt Bast and Haenen, {Guido R. M. M.}",
year = "2017",
month = "5",
doi = "10.1016/j.bbagen.2017.03.004",
language = "English",
volume = "1861",
pages = "1177--1189",
journal = "Biochimica et Biophysica Acta-general Subjects",
issn = "0304-4165",
publisher = "Elsevier Science",
number = "5",

}

TY - JOUR

T1 - Rutin protects against H2O2-triggered impaired relaxation of placental arterioles and induces Nrf2-mediated adaptation in Human Umbilical Vein Endothelial Cells exposed to oxidative stress

AU - Sthijns, Mireille M. J. P. E.

AU - Schiffers, Paul M.

AU - Janssen, Ger M.

AU - Lemmens, Kristien J. A.

AU - Ides, Bart

AU - Vangrieken, Philippe

AU - Bouwman, Freek G.

AU - Mariman, Edwin C.

AU - Pader, Irina

AU - Arner, Elias S. J.

AU - Johansson, Katarina

AU - Bast, Aalt

AU - Haenen, Guido R. M. M.

PY - 2017/5

Y1 - 2017/5

KW - Rutin

KW - Flavonoids

KW - Nrf2

KW - Adaptation

KW - Endothelial function

KW - NF-KAPPA-B

KW - DIETARY FLAVONOID QUERCETIN

KW - REACTIVE OXYGEN

KW - FLAVANOL (-)-EPICATECHIN

KW - FLUORESCENT-PROBES

KW - MEDIATED DILATION

KW - DYSFUNCTION

KW - GLUTATHIONE

KW - NRF2

KW - PATHWAY

U2 - 10.1016/j.bbagen.2017.03.004

DO - 10.1016/j.bbagen.2017.03.004

M3 - Article

VL - 1861

SP - 1177

EP - 1189

JO - Biochimica et Biophysica Acta-general Subjects

JF - Biochimica et Biophysica Acta-general Subjects

SN - 0304-4165

IS - 5

ER -