Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease

Peter J. Joris, Ronald P. Mensink*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


The effects of cis-monounsaturated fatty acids (cis-MUFAs) on the risk of coronary heart disease (CHD) and on CHD mortality are not clear. Also, dietary recommendations for cis-MUFA as derived by various organizations are not in agreement. Earlier studies have mainly focused on the effects of cis-MUFA on serum lipids and lipoproteins. More recent studies, however, have also addressed effects of cis-MUFA on other non-traditional CHD risk markers such as vascular function markers, postprandial vascular function, and energy intake and metabolism. Although well-designed randomized controlled trials with CHD events as endpoints are missing, several large prospective cohort studies have recently been published on the relationship between cis-MUFA and CHD risk. The aim of this paper is to review these new studies that have been published in the last 3 years on the effects of cis-MUFA on cardiovascular risk markers and CHD.
Original languageEnglish
Article number38
JournalCurrent Atherosclerosis Reports
Issue number7
Publication statusPublished - Jul 2016


  • Monounsaturated fatty acids
  • Oleic acid
  • Risk markers
  • Coronary heart disease
  • Cardiovascular disease

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