Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion

Amanda Santiago, Ligia Mendes Soares, Melissa Schepers, Humberto Milani, Tim Vanmierlo, Jos Prickaerts, Rubia M. de Oliveira

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)360-370
Number of pages11
JournalNeuropharmacology
Volume138
DOIs
Publication statusPublished - 1 Aug 2018

Keywords

  • Phosphodiesterase inhibitor
  • Roflumilast
  • Chronic cerebral hypoperfusion
  • Memory
  • CAROTID-ARTERY MODEL
  • COGNITIVE IMPAIRMENT
  • INHIBITOR ROLIPRAM
  • MOUSE MODEL
  • PHOSPHODIESTERASE-4 INHIBITORS
  • ALZHEIMERS-DISEASE
  • HYPERTENSIVE-RATS
  • NEURONAL DAMAGE
  • INDUCED DEFECTS
  • PDE4 INHIBITOR

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