RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA

Jose M. Gonzalez de Cozar, Mike Gerards, Eveliina Teeri, Jack George, Eric Dufour, Howard T. Jacobs*, Priit Joers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)4331-4344
Number of pages14
JournalJournal of Biological Chemistry
Volume294
Issue number12
DOIs
Publication statusPublished - 22 Mar 2019

Keywords

  • mitochondria
  • DNA replication
  • RNA
  • genomic instability
  • ribonuclease
  • heteroduplex
  • locomotor dysfunction
  • mtDNA
  • replication fork
  • RNase H
  • genome stability
  • insect rnh1
  • R-LOOPS
  • ALTERNATIVE OXIDASE
  • ACCESSORY SUBUNIT
  • POLYMERASE-GAMMA
  • BINDING PROTEIN
  • MTDNA
  • TFAM
  • EMBRYOGENESIS
  • MAINTENANCE
  • REGRESSION

Cite this

Gonzalez de Cozar, Jose M. ; Gerards, Mike ; Teeri, Eveliina ; George, Jack ; Dufour, Eric ; Jacobs, Howard T. ; Joers, Priit. / RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA. In: Journal of Biological Chemistry. 2019 ; Vol. 294, No. 12. pp. 4331-4344.
@article{195d16182e1f4757933363c941aedf0e,
title = "RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA",
keywords = "mitochondria, DNA replication, RNA, genomic instability, ribonuclease, heteroduplex, locomotor dysfunction, mtDNA, replication fork, RNase H, genome stability, insect rnh1, R-LOOPS, ALTERNATIVE OXIDASE, ACCESSORY SUBUNIT, POLYMERASE-GAMMA, BINDING PROTEIN, MTDNA, TFAM, EMBRYOGENESIS, MAINTENANCE, REGRESSION",
author = "{Gonzalez de Cozar}, {Jose M.} and Mike Gerards and Eveliina Teeri and Jack George and Eric Dufour and Jacobs, {Howard T.} and Priit Joers",
year = "2019",
month = "3",
day = "22",
doi = "10.1074/jbc.RA118.007015",
language = "English",
volume = "294",
pages = "4331--4344",
journal = "Journal of Biological Chemistry",
issn = "0021-9258",
publisher = "American Society for Biochemistry and Molecular Biology, Inc.",
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}

RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA. / Gonzalez de Cozar, Jose M.; Gerards, Mike; Teeri, Eveliina; George, Jack; Dufour, Eric; Jacobs, Howard T.; Joers, Priit.

In: Journal of Biological Chemistry, Vol. 294, No. 12, 22.03.2019, p. 4331-4344.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA

AU - Gonzalez de Cozar, Jose M.

AU - Gerards, Mike

AU - Teeri, Eveliina

AU - George, Jack

AU - Dufour, Eric

AU - Jacobs, Howard T.

AU - Joers, Priit

PY - 2019/3/22

Y1 - 2019/3/22

KW - mitochondria

KW - DNA replication

KW - RNA

KW - genomic instability

KW - ribonuclease

KW - heteroduplex

KW - locomotor dysfunction

KW - mtDNA

KW - replication fork

KW - RNase H

KW - genome stability

KW - insect rnh1

KW - R-LOOPS

KW - ALTERNATIVE OXIDASE

KW - ACCESSORY SUBUNIT

KW - POLYMERASE-GAMMA

KW - BINDING PROTEIN

KW - MTDNA

KW - TFAM

KW - EMBRYOGENESIS

KW - MAINTENANCE

KW - REGRESSION

U2 - 10.1074/jbc.RA118.007015

DO - 10.1074/jbc.RA118.007015

M3 - Article

VL - 294

SP - 4331

EP - 4344

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

IS - 12

ER -