RNase H1 promotes replication fork progression through oppositely transcribed regions of Drosophila mitochondrial DNA

Jose M. Gonzalez de Cozar, Mike Gerards, Eveliina Teeri, Jack George, Eric Dufour, Howard T. Jacobs*, Priit Joers

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)4331-4344
Number of pages14
JournalJournal of Biological Chemistry
Volume294
Issue number12
DOIs
Publication statusPublished - 22 Mar 2019

Keywords

  • mitochondria
  • DNA replication
  • RNA
  • genomic instability
  • ribonuclease
  • heteroduplex
  • locomotor dysfunction
  • mtDNA
  • replication fork
  • RNase H
  • genome stability
  • insect rnh1
  • R-LOOPS
  • ALTERNATIVE OXIDASE
  • ACCESSORY SUBUNIT
  • POLYMERASE-GAMMA
  • BINDING PROTEIN
  • MTDNA
  • TFAM
  • EMBRYOGENESIS
  • MAINTENANCE
  • REGRESSION

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