Risk Stratification by Ambulatory Blood Pressure Monitoring Across JNC Classes of Conventional Blood Pressure

Jana Brguljan-Hitij, Lutgarde Thijs, Yan Li, Tine W. Hansen, Jose Boggia, Yan-Ping Liu, Kei Asayama, Fang-Fei Wei, Kristina Bjorklund-Bodegard, Yu-Mei Gu, Takayoshi Ohkubo, Jorgen Jeppesen, Christian Torp-Pedersen, Eamon Dolan, Tatiana Kuznetsova, Katarzyna Stolarz-Skrzypek, Valerie Tikhonoff, Sofia Malyutina, Edoardo Casiglia, Yuri NikitinLars Lind, Edgardo Sandoya, Kalina Kawecka-Jaszcz, Jan Filipovsky, Yutaka Imai, Jiguang Wang, Eoin O'Brien, Jan A. Staessen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Web of Science)


BACKGROUND Guidelines propose classification of conventional blood pressure (CBP) into normotension (140/>90 mm Hg). METHODS To assess the potential differential contribution of ambulatory blood pressure (ABP) in predicting risk across CBP strata, we analyzed outcomes in 7,826 untreated people recruited from 11 populations. RESULTS During an 11.3-year period, 809 participants died (276 cardiovascular deaths) and 639, 383, and 225 experienced a cardiovascular, cardiac, or cerebrovascular event. Compared with normotension (n = 2,639), prehypertension (n = 3,076) carried higher risk (P = 0.13) across CBP categories. Of normotensive and prehypertensive participants, 7.5% and 29.3% had masked hypertension (daytime ABP >= 135/>= 85 mm Hg). Compared with true normotension (P
Original languageEnglish
Pages (from-to)956-965
JournalAmerican Journal of Hypertension
Issue number7
Publication statusPublished - Jul 2014


  • ambulatory blood pressure monitoring
  • blood pressure
  • hypertension
  • masked hypertension
  • population science
  • prehypertension
  • risk stratification

Cite this